Cao Saisai, Zhu Mengyi, Bi Ye
Department of Plastic Surgery, Peking University People's Hospital, Beijing, China.
Department of Dermatology, Peking University People's Hospital, Beijing, China.
J Cosmet Dermatol. 2024 Dec;23(12):4051-4056. doi: 10.1111/jocd.16519. Epub 2024 Aug 21.
This study was designed to evaluate the safety and efficacy of injections of concentrated growth factors (CGF) for hair growth promotion in androgenetic alopecia (AGA) patients.
A retrospective review of AGA patients treated with injections of CGF at our center from October 2021 to April 2023 was performed. A total of 3 injections were administered every 3-4 weeks apart, and evaluation were performed before the first injection and at 3 months, 6 months later. The outcomes were assessed by trichoscopy photomicrographs and the Global Aesthetic Improvement Scale (GAIS).
At 3 months after the first injection, the hair density and hair growth ratio were significantly improved. Significant improvements were found in GAIS score by both patients and independent doctors and the hair growth promotion was sustained for 6 months after first treatment.
According to this tiny single-arm trial, the use of CGF injection may help AGA by increasing terminal hair density and hair density. No severe topical or systemic adverse events occurred during the treatment.
本研究旨在评估注射浓缩生长因子（CGF）对雄激素性脱发（AGA）患者促进头发生长的安全性和有效性。
对2021年10月至2023年4月在本中心接受CGF注射治疗的AGA患者进行回顾性研究。每3 - 4周注射一次，共注射3次，分别在首次注射前、注射后3个月和6个月进行评估。通过毛囊镜显微照片和全球美学改善量表（GAIS）评估结果。
首次注射后3个月，头发密度和头发生长率显著改善。患者和独立医生评估的GAIS评分均有显著改善，且首次治疗后促进头发生长的效果持续6个月。
根据这项小型单臂试验，注射CGF可能通过增加终毛密度和头发密度来改善AGA。治疗期间未发生严重的局部或全身不良事件。
