Schaeffer Emily K, Price Charles T, Mulpuri Kishore
Department of Orthopaedic Surgery, British Columbia Children's Hospital, Vancouver, BC Canada.
Department of Orthopaedics, University of British Columbia, Vancouver, BC Canada.
Indian J Orthop. 2024 Jul 6;58(9):1297-1302. doi: 10.1007/s43465-024-01157-9. eCollection 2024 Sep.
Laterality and bilaterality have been reported as prognostic variables in developmental dysplasia of the hip (DDH) outcomes. However, there is little clarity across the literature on the reporting of laterality in developmental dysplasia of the hip (DDH) due to the variability in severity of the condition. It is widely accepted that the left hip is most frequently affected; however, the true incidence of unilateral left, unilateral right and bilateral cases can be hard to quantify and compare across studies. The purpose of this study was to examine laterality accounting for graded severity in a multi-centre, international prospective observational study of infants with hip dysplasia to demonstrate the complexity of this issue.
A multi-centre, prospective hip dysplasia database was analyzed from 2010 to April 2015. Baseline diagnosis was used to classify patients into a graded laterality category accounting for hip status within the DDH spectrum.
A total of 496 patients were included in the analysis; 328 were <6 months old at diagnosis and 168 were between 6 and 18 months old. Of these patients, 421 had at least one frankly dislocated hip. Unilateral left hip dislocations were most common, with 223 patients, followed by unilateral right and bilateral dislocations with 106 and 92 respectively. Stratifying these patients based on status of the contralateral hip, 54 unilateral left and 31 unilateral right dislocated patients also had a dysplastic or unstable contralateral hip. There were significantly fewer bilateral patients in the 6 to 18-month group ( = 0.0005). When classifying laterality by affected hip, bilaterality became the predominant finding, comprising 42% of all patients.
Findings from this multi-centre prospective study demonstrate the necessity to account for the graded severity in hip status when reporting DDH laterality. To accurately compare laterality across studies, a standardized, comprehensive classification should be established, as contralateral hip status may impact prognosis and treatment outcomes.
Level II Prognostic Study.
在发育性髋关节发育不良(DDH)的预后中,左右侧别及双侧受累情况已被报道为预后变量。然而,由于该病症严重程度的变异性,关于发育性髋关节发育不良(DDH)左右侧别报告的文献尚无明确结论。普遍认为左髋关节最常受累;然而,单侧左髋、单侧右髋及双侧病例的真实发病率在各项研究中可能难以量化和比较。本研究的目的是在一项针对髋关节发育不良婴儿的多中心、国际前瞻性观察研究中,考察考虑分级严重程度的左右侧别情况,以证明该问题的复杂性。
分析了2010年至2015年4月的多中心前瞻性髋关节发育不良数据库。根据基线诊断将患者分类到一个考虑DDH范围内髋关节状况的分级左右侧别类别中。
共有496例患者纳入分析;诊断时328例年龄小于6个月,168例年龄在6至18个月之间。这些患者中,421例至少有一侧髋关节明显脱位。单侧左髋关节脱位最为常见,有223例患者,其次是单侧右髋关节脱位和双侧髋关节脱位,分别为106例和92例。根据对侧髋关节状况对这些患者进行分层,54例单侧左髋关节脱位和31例单侧右髋关节脱位患者的对侧髋关节也存在发育不良或不稳定情况。6至18个月组的双侧受累患者明显较少(P = 0.0005)。按受累髋关节分类左右侧别时,双侧受累成为主要情况,占所有患者的42%。
这项多中心前瞻性研究的结果表明,在报告DDH左右侧别时,有必要考虑髋关节状况的分级严重程度。为了在各项研究之间准确比较左右侧别情况,应建立标准化、全面的分类,因为对侧髋关节状况可能影响预后和治疗结果。
II级预后研究。