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慢性阻塞性肺疾病急性加重的早期检测与预测

Early detection and prediction of acute exacerbation of chronic obstructive pulmonary disease.

作者信息

Zhang Jing, Chen Fangman, Wang Yongli, Chen Yahong

机构信息

Department of Pulmonary and Critical Care Medicine, Peking University Third Hospital, Beijing 100191, China.

Research Center for Chronic Airway Disease, Peking University Health Science Center, Beijing 100191, China.

出版信息

Chin Med J Pulm Crit Care Med. 2023 Jun 2;1(2):102-107. doi: 10.1016/j.pccm.2023.04.004. eCollection 2023 Jun.

DOI:10.1016/j.pccm.2023.04.004
PMID:39170822
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11332833/
Abstract

Chronic Obstructive Pulmonary Disease (COPD) is characterized by persistent respiratory symptoms and airflow limitation. Acute exacerbation of COPD (AECOPD) is an acute worsening of respiratory symptoms, which needs additional treatment and can result in worsening health status, increasing risks of hospitalization and mortality. Therefore, it is necessary to early recognize and diagnose exacerbations of COPD. This review introduces the updated definition of COPD exacerbations, the current clinical assessment tools, and the current potential biomarkers. The application of mobile health care in COPD management for early identification and diagnosis is also included in this review.

摘要

慢性阻塞性肺疾病(COPD)的特征是持续的呼吸道症状和气流受限。慢性阻塞性肺疾病急性加重(AECOPD)是呼吸道症状的急性恶化,需要额外治疗,可导致健康状况恶化、住院风险和死亡率增加。因此,早期识别和诊断慢性阻塞性肺疾病急性加重非常必要。本综述介绍了慢性阻塞性肺疾病急性加重的最新定义、当前的临床评估工具以及当前潜在的生物标志物。本综述还包括移动医疗在慢性阻塞性肺疾病管理中用于早期识别和诊断的应用。

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本文引用的文献

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The Emerging Clinical Significance of the Red Cell Distribution Width as a Biomarker in Chronic Obstructive Pulmonary Disease: A Systematic Review.红细胞分布宽度作为慢性阻塞性肺疾病生物标志物的新出现的临床意义:一项系统评价
J Clin Med. 2022 Sep 25;11(19):5642. doi: 10.3390/jcm11195642.
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Lancet. 2022 Sep 17;400(10356):921-972. doi: 10.1016/S0140-6736(22)01273-9. Epub 2022 Sep 5.
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Fibrinogen, a Promising Marker to Evaluate Severity and Prognosis of Acute Exacerbation of Chronic Obstructive Pulmonary Disease: A Retrospective Observational Study.纤维蛋白原:评估慢性阻塞性肺疾病急性加重严重程度和预后的有前途的标志物:一项回顾性观察性研究。
Int J Chron Obstruct Pulmon Dis. 2022 Jun 3;17:1299-1310. doi: 10.2147/COPD.S361929. eCollection 2022.
4
Internet of things-based home noninvasive ventilation in COPD patients with hypercapnic chronic respiratory failure: study protocol for a randomized controlled trial.基于物联网的 COPD 并高碳酸血症性慢性呼吸衰竭患者家庭无创通气:一项随机对照试验的研究方案。
Trials. 2022 May 12;23(1):393. doi: 10.1186/s13063-022-06372-z.
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Life (Basel). 2022 Mar 29;12(4):499. doi: 10.3390/life12040499.
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