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一名成年患者的斜坡骨髓炎:病例报告

Clival Osteomyelitis in an Adult Patient: A Case Report.

作者信息

Shinde Vinod, Kothari Aishwarya, Ingale Mayur, Devi Putta Sunanda

机构信息

Otorhinolaryngology, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Dr. D. Y. Patil Vidyapeeth (Deemed to be University) Pune, Pune, IND.

出版信息

Cureus. 2024 Jul 21;16(7):e65055. doi: 10.7759/cureus.65055. eCollection 2024 Jul.

DOI:10.7759/cureus.65055
PMID:39171050
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11335692/
Abstract

Clival osteomyelitis is an uncommon skull base infection that mostly affects elderly diabetics and is frequently caused by malignant otitis externa or paranasal sinus infections. It manifests as severe otalgia, fever, auditory fullness, and purulent otorrhea. Clinical history, physical examination, test data, radiographic findings, and pathogen identification all contribute to a diagnosis. Treatment consists of extended intravenous broad-spectrum antibiotics, with severe cases necessitating surgical debridement. We present a case of a 20-year-old girl with bilateral ear discharge, nasal blockage, and purulent rhinorrhea, as well as a dull neck ache increased by extension. An MRI revealed osteomyelitis in the clivus and right atlanto-occipital joint. The clival abscess was drained transnasally using endoscopic techniques. Microbiological tests revealed Streptococcus intermedius. The post-operative recovery was uneventful, with extended antibiotic therapy. Early identification and treatment are critical for preventing serious consequences, as illustrated in this case, where surgical and antibiotic care improves patient outcomes.

摘要

斜坡骨髓炎是一种罕见的颅底感染,主要影响老年糖尿病患者,常由恶性外耳道炎或鼻窦感染引起。其表现为严重耳痛、发热、耳闷和脓性耳漏。临床病史、体格检查、检测数据、影像学检查结果和病原体鉴定均有助于诊断。治疗包括长期静脉注射广谱抗生素,严重病例需要手术清创。我们报告一例20岁女孩,有双侧耳漏、鼻塞和脓性鼻漏,以及伸展时加重的颈部钝痛。磁共振成像显示斜坡和右寰枕关节骨髓炎。采用内镜技术经鼻引流斜坡脓肿。微生物检测显示为中间型链球菌。术后恢复顺利,进行了延长疗程的抗生素治疗。早期识别和治疗对于预防严重后果至关重要,如本病例所示,手术和抗生素治疗改善了患者的预后。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd7/11335692/676b1fef9aa5/cureus-0016-00000065055-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd7/11335692/1d3fc119775a/cureus-0016-00000065055-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd7/11335692/7e4bd9349479/cureus-0016-00000065055-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd7/11335692/676b1fef9aa5/cureus-0016-00000065055-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd7/11335692/1d3fc119775a/cureus-0016-00000065055-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd7/11335692/7e4bd9349479/cureus-0016-00000065055-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9fd7/11335692/676b1fef9aa5/cureus-0016-00000065055-i03.jpg

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本文引用的文献

1
A Case of Adult Clival Osteomyelitis.成人颅底骨髓炎 1 例报告。
J Investig Med High Impact Case Rep. 2022 Jan-Dec;10:23247096221101858. doi: 10.1177/23247096221101858.
2
A Comprehensive Review of Skull Base Osteomyelitis: Diagnostic and Therapeutic Challenges among Various Presentations.颅底骨髓炎综合综述:不同临床表现下的诊断与治疗挑战
Asian J Neurosurg. 2018 Oct-Dec;13(4):959-970. doi: 10.4103/ajns.AJNS_90_17.
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Advanced Imaging Techniques in Skull Base Osteomyelitis Due to Malignant Otitis Externa.恶性外耳道炎所致颅底骨髓炎的先进成像技术
Curr Radiol Rep. 2018;6(1):3. doi: 10.1007/s40134-018-0263-y. Epub 2018 Jan 22.
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Temporomandibular joint disorder from skull-base osteomyelitis: a case report.颅底骨髓炎所致颞下颌关节紊乱:一例报告
Maxillofac Plast Reconstr Surg. 2015 Oct 31;37(1):39. doi: 10.1186/s40902-015-0041-1. eCollection 2015 Dec.
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Laryngoscope. 2014 May;124(5):1083-7. doi: 10.1002/lary.24440. Epub 2013 Nov 7.
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Skull Base. 2009 Jul;19(4):247-54. doi: 10.1055/s-0028-1115325.
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Osteomyelitis in the head and neck.头颈部骨髓炎
Acta Otolaryngol. 2007 Feb;127(2):194-205. doi: 10.1080/00016480600818054.
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