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表现为房室传导阻滞和心内肿块的心脏结节病:病例报告及文献综述

Cardiac sarcoidosis manifesting with atrioventricular block and intracardiac masses: case report and literature review.

作者信息

Newman Noah, Garcia Mariana, Ayele Frehiywot, Gandiga Prateek, Bhatt Kunal

机构信息

Department of Cardiology Atlanta, Emory University School of Medicine, 100 Woodruff Circle, Atlanta, GA 30322, USA.

Department of Rheumatology Atlanta, Emory University School of Medicine, Atlanta, GA, USA.

出版信息

Eur Heart J Case Rep. 2024 Aug 12;8(8):ytae407. doi: 10.1093/ehjcr/ytae407. eCollection 2024 Aug.

DOI:10.1093/ehjcr/ytae407
PMID:39171133
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11337001/
Abstract

BACKGROUND

Cardiac sarcoidosis (CS) typically manifests with atrioventricular block (AVB), ventricular arrhythmias, or heart failure. Intracardiac masses due to CS are rare, and there is both a paucity of evidence and guidelines of how manage them.

CASE SUMMARY

We describe a 45-year-old woman who presented with palpitations and dyspnoea on exertion found to have second-degree AVB. Further work-up noted two right atrial masses that, following excision and pathology, were identified as CS. Within several months of immunosuppressive treatment, imaging and device reports demonstrated mass resolution without arrhythmia recurrence.

DISCUSSION

Intracardiac masses are a rare manifestation of CS. Immunosuppressive therapy remains the mainstay of treatment, with consideration of mass resection for diagnostic purposes.

摘要

背景

心脏结节病(CS)通常表现为房室传导阻滞(AVB)、室性心律失常或心力衰竭。CS导致的心内肿块罕见,且关于如何处理它们的证据和指南都很缺乏。

病例摘要

我们描述了一名45岁女性,她因劳力性心悸和呼吸困难就诊,被发现有二度AVB。进一步检查发现两个右心房肿块,切除并经病理检查后,确诊为CS。在免疫抑制治疗的几个月内,影像学和设备报告显示肿块消退,且心律失常未复发。

讨论

心内肿块是CS的罕见表现。免疫抑制治疗仍然是主要的治疗方法,出于诊断目的可考虑切除肿块。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f2a/11337001/a582d3996d7f/ytae407f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f2a/11337001/85e257b99e13/ytae407f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f2a/11337001/aa744c420cd5/ytae407f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f2a/11337001/a582d3996d7f/ytae407f3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f2a/11337001/85e257b99e13/ytae407f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f2a/11337001/aa744c420cd5/ytae407f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8f2a/11337001/a582d3996d7f/ytae407f3.jpg

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Cardiac sarcoidosis accompanied by a tumor-like blush on coronary angiography.
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Eur Respir J. 2022 May 5;59(5). doi: 10.1183/13993003.00449-2021. Print 2022 May.
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