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输血医学中梅毒风险的“新老”问题:血清及ACD稳定剂在不同温度下对梅毒螺旋体(Nichols株)感染性的影响

["Old new" problem of the lues risk in transfusion medicine: the effect of the serum and ACD stabilizer at different temperatures on the infectiosity of Treponema pallidium (Nichols strain)].

作者信息

Müller F, von Eisenhart-Rothe B, Busch H

出版信息

Infusionsther Klin Ernahr. 1979 Oct;6(5):306-10.

PMID:391712
Abstract

The portion of warm and fresh blood transfusions had increased obviously. This is accompanied by a decrease of the restrictive period of the former 72 and the presently 48 hours for blood units to be transfused. Therefore, the danger of a symphilis transmitted by transfusion is impending again. This is realized insufficiently and the syphilis may occur, if blood is drawn in the seronegative phase of the primary stage of syphilis and transfused within the restrictive period. Model trials on the infectivity of Treponema pallidum revealed that the syphilis cannot be transmitted by blood and its derivates drawn in the seronegative phase after storage at 4 degrees C for 24 hours. Therefore, the reduction of the restrictive period to 48 hours is justified.

摘要

温热新鲜血液输注的比例明显增加。这伴随着之前72小时和目前48小时的血液输注限制期的缩短。因此,输血传播梅毒的危险再次迫在眉睫。这一点尚未得到充分认识,如果在梅毒一期血清阴性阶段采血并在限制期内输血,就可能发生梅毒。梅毒螺旋体感染性的模型试验表明,在4℃储存24小时后处于血清阴性阶段采集的血液及其衍生物不会传播梅毒。因此,将限制期缩短至48小时是合理的。

相似文献

6
[Syphilis and blood transfusion].[梅毒与输血]
Rev Fr Transfus Immunohematol. 1977 Jun;20(2):287-308. doi: 10.1016/s0338-4535(77)80094-9.

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