Department of Otorhinolaryngology Head and Neck Surgery, Shanghai Sixth People's Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, 600 Yishan Road, Shanghai, China.
Shanghai Key Laboratory of Sleep Disordered Breathing, 600 Yishan Road, Shanghai, China.
Eur Arch Otorhinolaryngol. 2024 Nov;281(11):5831-5839. doi: 10.1007/s00405-024-08812-9. Epub 2024 Aug 22.
To investigate the nasal cycle (NC) during sleep in healthy individuals without nasal obstruction or obstructive sleep apnoea via a flexible wearable respiratory monitoring system in a continuous and real-time manner.
NC during sleep was continuously measured in 30 healthy individuals (15 women, 15 men) via long-term sleep respiratory monitoring system, while sleep stage and body position were simultaneously recorded via polysomnography (PSG). The number of NC transitions and positional changes were documented each night. Additionally, time intervals between NC transitions and their closest positional changes during sleep were meticulously recorded to investigate potential correlations between them.
A total of 86.7% of the participants displayed the classic NC, with a mean duration of 6.43 ± 2.33 h. Nightly observations revealed an average occurrence of 2.19 ± 0.40 NC transitions, predominantly occurring during REM stage (68.4%), and 9.15 ± 7.77 postural changes. Analysis of the intervals between NC transitions and positional changes revealed an average absolute value of 27.72 ± 10.85 min, with a substantial 56.4% exceeding 30 min, indicating a non-obvious sequence order among them.
NC can be measured in a continuous and real-time manner, the transitions occur mainly during the REM stage. However, we have not identified a clear correlation between NC transition and positional change.
通过长期睡眠呼吸监测系统，以连续和实时的方式，研究健康个体在无鼻阻塞或阻塞性睡眠呼吸暂停的情况下睡眠期间的鼻周期（NC）。
通过多导睡眠图（PSG）同时记录睡眠阶段和体位，对 30 名健康个体（15 名女性，15 名男性）进行睡眠期间的 NC 连续测量。每晚记录 NC 转变的次数和体位变化。此外，还详细记录了 NC 转变之间及其在睡眠期间最接近的体位变化之间的时间间隔，以研究它们之间的潜在相关性。
共有 86.7%的参与者表现出经典的 NC，平均持续时间为 6.43±2.33 h。夜间观察显示，平均发生 2.19±0.40 次 NC 转变，主要发生在 REM 阶段（68.4%），体位变化 9.15±7.77 次。对 NC 转变和体位变化之间的间隔进行分析，得出的平均绝对值为 27.72±10.85 min，其中 56.4%显著超过 30 min，表明它们之间的顺序不明显。
可以连续和实时地测量 NC，转变主要发生在 REM 阶段。然而，我们尚未确定 NC 转变与体位变化之间的明显相关性。
