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有和没有进行心肺运动试验(CPET)的患者结局比较。

A Comparison of Outcome in Patient With and Without Undergoing Cardiopulmonary Exercise Testing (CPET).

机构信息

Department of Vascular Surgery, University Hospitals Birmingham, Birmingham, UK.

出版信息

Vasc Endovascular Surg. 2024 Nov;58(8):862-865. doi: 10.1177/15385744241277053. Epub 2024 Aug 22.

DOI:10.1177/15385744241277053
PMID:39172489
Abstract

BACKGROUND

Cardiopulmonary exercise testing (CPET) is a preoperative risk stratification tool providing an objective measure of fitness and functional capacity. There is however little evidence on the use of this compared to non-physiological test in vascular surgery despite its current use. This study investigates whether CPET perioperatively has value alongside non-physiological testing for patients undergoing elective open abdominal aortic aneurysm (AAA) repair.

METHOD

Retrospective data was collected at 2 vascular centres between 2015-2019 in a CPET centre vs non-CPET centre in patients undergoing elective AAA repair. Outcomes measured included: length of stay in an intensive care unit (ICU); total length of stay; post-operative complications and acute kidney injury (AKI). Statistical analysis was performed using IBM SPSS software.

RESULTS

There were 38 patients at each centre. The mean duration of stay in ICU for patients in CPET centre was 2.5 ± 2.13 days whilst in non-CPET centre it was 3.68 ± 4.08 days ( = 0.05). The mean duration of stay in ICU and total length of stay was significantly shorter in CPET centre ( = 0.05 and = 0.015 respectively). Mortality in CPET centre was 2.63% and 5.26% in non-CPET centre (not significant). The number of patients developing AKI post-operatively was 13.61% in CPET vs 28.95% in non-CPET centre.

CONCLUSION

CPET tested patients have statistically significant lower length of total and ICU stay compared to non-CPET patients. CPET is therefore a useful adjunct in selecting patients for open surgery compared to non-physiological testing. This study provides some evidence on the use of this routinely but not validated assessment tool in aortic aneurysm repair.

摘要

背景

心肺运动测试(CPET)是一种术前风险分层工具,提供了对健康和功能能力的客观测量。然而,尽管目前正在使用,但与非生理测试相比,血管外科领域使用这种工具的证据很少。本研究调查了在选择性开放腹主动脉瘤(AAA)修复中,CPET 围手术期与非生理测试联合使用是否具有价值。

方法

在 2015 年至 2019 年期间,在 CPET 中心和非 CPET 中心的 2 个血管中心收集了回顾性数据,这些中心的患者均接受选择性 AAA 修复。测量的结果包括:重症监护病房(ICU)的住院时间;总住院时间;术后并发症和急性肾损伤(AKI)。使用 IBM SPSS 软件进行统计分析。

结果

每个中心各有 38 例患者。CPET 中心患者 ICU 住院时间的平均值为 2.5 ± 2.13 天,而非 CPET 中心为 3.68 ± 4.08 天( = 0.05)。CPET 中心 ICU 和总住院时间的平均值明显更短( = 0.05 和 = 0.015 分别)。CPET 中心的死亡率为 2.63%,而非 CPET 中心为 5.26%(无显著性差异)。CPET 中心术后发生 AKI 的患者有 13.61%,而非 CPET 中心有 28.95%。

结论

CPET 测试患者的总住院时间和 ICU 住院时间明显短于非 CPET 患者。因此,与非生理测试相比,CPET 是选择开放手术患者的有用辅助手段。本研究为主动脉瘤修复中使用该常规但未经验证的评估工具提供了一些证据。

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