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择期血管内动脉瘤修复术前心肺运动试验和超声心动图的作用。

The role of cardiopulmonary exercise testing and echocardiography prior to elective endovascular aneurysm repair.

作者信息

Straw S, Waduud M A, Drozd M, Warman P, Bailey M A, Hammond C J, Abdel-Rahman Sed, Witte K K, Scott Dja

机构信息

University of Leeds, UK.

Leeds Teaching Hospitals NHS Trust, UK.

出版信息

Ann R Coll Surg Engl. 2020 May;102(5):383-390. doi: 10.1308/rcsann.2020.0045. Epub 2020 Apr 1.

Abstract

INTRODUCTION

Cardiopulmonary exercise testing (CPET) and transthoracic echocardiography (TTE) are common preparative investigations prior to elective endovascular aneurysm repair (EVAR). Whether these investigations can predict survival following EVAR and contribute to shared decision making is unknown.

METHODS

Patients who underwent EVAR at a tertiary centre between June 2007 and December 2014 were identified from the National Vascular Registry. Variables obtained from preoperative investigations were assessed for their association with survival at three years. Regression analysis was used to determine variables that independently predicted survival at three years.

RESULTS

A total of 199 patients underwent EVAR during the study period. Of these, 120 had preoperative CPET and 123 had TTE. Lower forced expiratory ventilation (FEV), ratio of FEV to forced vital capacity, work at peak oxygen consumption and higher ventilatory equivalent for carbon dioxide were associated with increased mortality. Variables obtained from TTE were not associated with survival at three years although there was a low incidence of left ventricular systolic dysfunction and significant valvular disease in this cohort.

CONCLUSIONS

CPET might be a useful adjunct to assist in shared decision making in patients undergoing elective EVAR and may influence anaesthetic technique. TTE does not appear to be able to discriminate between high and low risk individuals. However, a low rate of significant ventricular dysfunction and valvular disease in patients undergoing elective EVAR may account for these findings.

摘要

引言

心肺运动试验(CPET)和经胸超声心动图(TTE)是择期血管内动脉瘤修复术(EVAR)前常见的准备性检查。这些检查能否预测EVAR后的生存率并有助于共同决策尚不清楚。

方法

从国家血管登记处识别出2007年6月至2014年12月在一家三级中心接受EVAR的患者。评估术前检查获得的变量与三年生存率的相关性。采用回归分析确定独立预测三年生存率的变量。

结果

在研究期间,共有199例患者接受了EVAR。其中,120例患者术前行CPET,123例患者术前行TTE。较低的用力呼气通气量(FEV)、FEV与用力肺活量的比值、峰值耗氧量时的做功以及较高的二氧化碳通气当量与死亡率增加相关。尽管该队列中左心室收缩功能障碍和严重瓣膜病的发生率较低,但从TTE获得的变量与三年生存率无关。

结论

CPET可能是一种有用的辅助手段,有助于在接受择期EVAR的患者中进行共同决策,并可能影响麻醉技术。TTE似乎无法区分高风险和低风险个体。然而,择期EVAR患者中显著心室功能障碍和瓣膜病的发生率较低可能解释了这些结果。

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