Emerg Infect Dis. 2024 Sep;30(9):1841-1849. doi: 10.3201/eid3009.231448.
Nontuberculous mycobacterial pulmonary disease (NTM-PD) prevalence is a rising public health concern. We assessed the long-term healthcare systems perspective of costs incurred by 147 NTM-PD patients at a tertiary hospital in South Korea. Median cumulative total medical cost in managing NTM-PD patients was US $5,044 (interquartile range US $3,586-$9,680) over 49.7 months (interquartile range 33.0-68.2 months) of follow-up. The major cost drivers were diagnostic testing and medication, accounting for 59.6% of total costs. Higher costs were associated with hospitalization for Mycobacterium abscessus infection and pulmonary comorbidities. Of the total medical care costs, 50.2% were patient co-payments resulting from limited national health insurance coverage. As South Korea faces significant problems of poverty during old age and increasing NTM-PD prevalence, the financial and socio-economic burden of NTM-PD may become a major public health concern that should be considered with regard to adequate strategies for NTM-PD patients.
非结核分枝杆菌肺病（NTM-PD）的患病率是一个日益受到关注的公共卫生问题。我们评估了韩国一家三级医院 147 名 NTM-PD 患者的长期医疗系统成本视角。在 49.7 个月（33.0-68.2 个月）的随访中，管理 NTM-PD 患者的中位累计总医疗费用为 5044 美元（四分位距，3586-9680 美元）。主要的成本驱动因素是诊断测试和药物治疗，占总费用的 59.6%。更高的费用与住院治疗脓肿分枝杆菌感染和肺部合并症有关。在总医疗费用中，有 50.2%是由于国家健康保险覆盖范围有限而由患者自付的费用。随着韩国在老年时期面临严重的贫困问题和 NTM-PD 患病率的增加，NTM-PD 的经济和社会经济负担可能成为一个主要的公共卫生问题，应该考虑为 NTM-PD 患者制定适当的策略。
