Department of Cardiology, G.B. Pant Institute of Post Graduate Medical Education and Research, New Delhi, India.
Department of Cardiology, G.B. Pant Institute of Post Graduate Medical Education and Research, New Delhi, India.
Am J Cardiol. 2024 Oct 15;229:47-55. doi: 10.1016/j.amjcard.2024.08.010. Epub 2024 Aug 22.
Culotte stenting is an effective strategy for left main coronary artery bifurcation lesions. Increased side branch ostial restenosis is the main drawback of culotte stenting. This is due to a napkin ring or potential gap produced at the ostium of the side branch. A bench study by Toth et al has shown that additional sequential kissing balloon dilation before main vessel stenting can prevent this deformity. We report immediate and short-term results of double kissing (DK) mini-culotte stenting with a 1-year angiographic follow-up. Between March 2020 and December 2022, 45 patients with distal left main (LM) disease underwent DK mini-culotte stenting at our center under optical coherence tomography guidance. Of 45 patients (male: 35 (77.77%); mean age: 63.67 ± 4.94 years), chronic coronary artery syndrome was present in 26 (57.8%) and unstable angina in the remainder. All lesions were Medina (1,1,1), (0,1,1), or (1,0,1), with a median Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery (SYNTAX) score of 28 (interquartile range 23 to 29). All procedures were technically successful with no adverse clinical events (death, myocardial infarction, or stent thrombosis). Under optical coherence tomography guidance, adequate minimal stent area of 13.28 ± 0.77 mm, 8.25 ± 0.29 mm, and 7.54 ± 0.45 mm was achieved in LM, left anterior descending, and left circumflex, respectively. Adequate stent expansion of >80% was achieved in all cases. At the end of 1 year, the incidence of major adverse cardiovascular events was 2.2%. Furthermore, restenosis of the side branch developed in 1 patient (2.2%), which was managed conservatively. DK mini-culotte stenting in the distal LM bifurcation has shown promising results and is effective in preventing side branch stent deformation and its sequelae of in-stent restenosis.
采用 Culotte 支架术治疗左主干冠状动脉分叉病变效果显著。但边支开口再狭窄是 Culotte 支架术的主要缺点,这是由于边支开口处形成了“餐巾环”或潜在的“缝隙”。Toth 等人的一项体外研究表明,在主血管支架置入前,额外采用序贯对吻球囊扩张术可预防这种变形。我们报告了在光学相干断层成像(OCT)指导下,采用双对吻(DK)迷你 Culotte 支架术治疗的即刻和短期结果,并进行了为期 1 年的血管造影随访。2020 年 3 月至 2022 年 12 月,在我院接受 DK 迷你 Culotte 支架术治疗的 45 例远端左主干(LM)病变患者,男性 35 例(77.77%),平均年龄 63.67±4.94 岁,慢性冠状动脉综合征 26 例(57.8%),不稳定型心绞痛 19 例。所有病变均为 Medina 1,1,1(0,1,1)或 1,0,1,中位数 SYNTAX 评分 28 分(23~29 分)。所有手术均获技术成功,无不良临床事件(死亡、心肌梗死或支架血栓形成)。在 OCT 指导下,LM、前降支和左旋支的最小支架面积分别达到 13.28±0.77mm、8.25±0.29mm 和 7.54±0.45mm,支架扩张率>80%。1 年后,主要不良心血管事件发生率为 2.2%。此外,1 例(2.2%)患者出现边支再狭窄,予以保守治疗。DK 迷你 Culotte 支架术治疗远端 LM 分叉病变效果良好,可有效预防边支支架变形及其支架内再狭窄的并发症。