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COVID-19 大流行前后院内心脏骤停存活率:表现更好的医院是否一直表现出色?

In-hospital cardiac arrest survival before and after the COVID-19 pandemic: Have higher performing hospitals stayed high-performing?

机构信息

Saint Luke's Mid America Heart Institute, Kansas City, MO, USA; University of Missouri-Kansas City, Kansas City, MO, USA.

Saint Luke's Mid America Heart Institute, Kansas City, MO, USA.

出版信息

Resuscitation. 2024 Oct;203:110374. doi: 10.1016/j.resuscitation.2024.110374. Epub 2024 Aug 20.

Abstract

BACKGROUND

Survival for in-hospital cardiac arrest (IHCA) has declined since the COVID-19 pandemic. Because the burden of COVID-19 was uneven throughout the U.S., it remains unknown if top-performer hospitals in IHCA survival have remained top-performers since the pandemic.

METHODS

Within Get With The Guidelines®-Resuscitation, we identified hospitals with at least 2 years of registry participation pre-pandemic (2017-2019) and post-pandemic (July 2020-2022) and with at least 20 IHCA cases in both periods. Using multivariable hierarchical models with hospital as a random effect and adjusting for patient and arrest characteristics, we calculated risk-standardized survival rates to discharge (RSSR) for IHCA at each hospital during the pre- and post-pandemic periods. We then assessed the correlation between a hospital's pre-pandemic and post-pandemic RSSR for IHCA, and whether the correlation differed by the proportion of Black or Hispanic IHCA patients at each hospital.

RESULTS

A total of 243 hospitals were included, comprising 122,561 IHCAs (pre-pandemic: 57,601; post-pandemic: 64,960). Pre-pandemic, the mean RSSR was 26.8% (SD, 5.2%) whereas the mean RSSR post-pandemic was 21.7% (SD, 5.5%). There was good correlation between a hospital's pre- and post-pandemic RSSR: correlation of 0.55. When hospitals were categorized into tertiles based on the proportion of their IHCA patients who were Black or Hispanic, this correlation remained similar: 0.48, 0.68, and 0.45 (interaction P-value: 0.69) for hospitals in the upper, middle and lower tertiles, respectively.

CONCLUSION

Although the COVID-19 pandemic affected the U.S. unevenly, there was good correlation in a hospital's performance for IHCA survival before and after the pandemic, even at hospitals caring for a larger proportion of Black and Hispanic patients. Future studies are needed to understand what characteristics of high-performing hospitals pre-pandemic allowed many to continue to excel in the post-pandemic period.

摘要

背景

自 COVID-19 大流行以来,院内心搏骤停(IHCA)的存活率有所下降。由于 COVID-19 的负担在美国各地不均衡,因此尚不清楚 IHCA 存活率排名靠前的医院在大流行后是否仍然表现出色。

方法

在 Get With The Guidelines®-Resuscitation 中,我们确定了至少在大流行前(2017-2019 年)和大流行后(2020 年 7 月至 2022 年)有至少 2 年登记参与记录且在两个时期都至少有 20 例 IHCA 病例的医院。我们使用以医院为随机效应的多变量分层模型,并根据患者和发病特征进行调整,计算了每个医院在大流行前和大流行后的 IHCA 风险标准化生存率(RSSR)。然后,我们评估了医院 IHCA 的大流行前和大流行后 RSSR 之间的相关性,以及相关性是否因每个医院的黑人和西班牙裔 IHCA 患者比例而异。

结果

共纳入 243 家医院,共 122561 例 IHCA(大流行前:57601 例;大流行后:64960 例)。大流行前,平均 RSSR 为 26.8%(标准差,5.2%),而大流行后平均 RSSR 为 21.7%(标准差,5.5%)。医院的大流行前和大流行后 RSSR 之间存在良好的相关性:相关性为 0.55。当根据其 IHCA 患者中黑人和西班牙裔患者的比例将医院分为三分位数时,这种相关性仍然相似:上、中、下三分位数的医院分别为 0.48、0.68 和 0.45(交互 P 值:0.69)。

结论

尽管 COVID-19 大流行在美国的影响不均衡,但即使在治疗黑人和西班牙裔患者比例较大的医院,医院 IHCA 生存率的大流行前和大流行后表现仍存在良好的相关性。需要进一步的研究来了解大流行前高绩效医院的哪些特征使许多医院能够在大流行后继续表现出色。

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