Li Jin, Cao Dan, Li Wenlu, Sarnthein Johannes, Jiang Tianzi
School of Psychology, Capital Normal University, Beijing, 100048, China.
School of Psychology, Capital Normal University, Beijing, 100048, China; Brainnetome Center, Institute of Automation, Chinese Academy of Sciences, Beijing 100190, China.
Trends Cogn Sci. 2024 Dec;28(12):1132-1144. doi: 10.1016/j.tics.2024.07.008. Epub 2024 Aug 21.
The study of human working memory (WM) holds significant importance in neuroscience; yet, exploring the role of the medial temporal lobe (MTL) in WM has been limited by the technological constraints of noninvasive methods. Recent advancements in human intracranial neural recordings have indicated the involvement of the MTL in WM processes. These recordings show that different regions of the MTL are involved in distinct aspects of WM processing and also dynamically interact with each other and the broader brain network. These findings support incorporating the MTL into models of the neural basis of WM. This integration can better reflect the complex neural mechanisms underlying WM and enhance our understanding of WM's flexibility, adaptability, and precision.
人类工作记忆（WM）的研究在神经科学中具有重要意义；然而，由于非侵入性方法的技术限制，探索内侧颞叶（MTL）在工作记忆中的作用一直受到限制。人类颅内神经记录的最新进展表明，MTL参与了工作记忆过程。这些记录显示，MTL的不同区域参与了工作记忆处理的不同方面，并且还相互之间以及与更广泛的脑网络动态相互作用。这些发现支持将MTL纳入工作记忆神经基础的模型中。这种整合可以更好地反映工作记忆背后复杂的神经机制，并增强我们对工作记忆的灵活性、适应性和精确性的理解。
