Laboratory for Advanced Research in Natural and Synthetic Chemistry, KET's V.G. Vaze College, Mithagar Road, Mulund (E), Mumbai, 400081, Maharashtra, India.
Crop Research Institute, Drnovska 507, 161 06, Prague 6, Ruzyne, Czech Republic.
Environ Sci Pollut Res Int. 2024 Aug;31(40):53135-53139. doi: 10.1007/s11356-024-34719-3. Epub 2024 Aug 23.
Musca domestica L., a common housefly, and Culex quinquefasciatus mosquito are quite well-known pests that can transfer a wide range of diseases to humans as well as animals. In this study, various isoborneol derivatives including esters, ethers, and thioethers were synthesized from isoborneol under mild conditions. These derivatives were evaluated for inhibition of house-fly M. domestica adults and Cx. quinquefasciatus larvae. Two of the synthesized isoborneol ester derivatives (2 and 3) showed good activity against both insect species. Additional two derivatives (6 and 9) were active against M. domestica L., and the derivatives (1-3, 8) were active against Cx. quinquefasciatus larvae.
家蝇（Musca domestica L.）和致倦库蚊（Culex quinquefasciatus）是两种常见的害虫，它们可以将多种疾病传播给人类和动物。在这项研究中，我们在温和条件下从异胡薄荷醇合成了各种异胡薄荷醇衍生物，包括酯、醚和硫醚。我们评估了这些衍生物对家蝇成虫和致倦库蚊幼虫的抑制作用。两种合成的异胡薄荷醇酯衍生物（2 和 3）对两种昆虫均表现出良好的活性。另外两种衍生物（6 和 9）对家蝇具有活性，而衍生物（1-3、8）对致倦库蚊幼虫具有活性。
