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了解经前病情加重：探寻月经周期与精神疾病的交叉点。

Understanding premenstrual exacerbation: navigating the intersection of the menstrual cycle and psychiatric illnesses.

作者信息

Lin Jenny, Nunez Christine, Susser Leah, Gershengoren Liliya

机构信息

Department of Psychiatry, New York University, New York, NY, United States.

Department of Psychiatry, Weill Cornell Medicine, White Plains, NY, United States.

出版信息

Front Psychiatry. 2024 Aug 8;15:1410813. doi: 10.3389/fpsyt.2024.1410813. eCollection 2024.

DOI:10.3389/fpsyt.2024.1410813
PMID:39176230
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11338788/
Abstract

Premenstrual exacerbation of an existing psychiatric disorder refers to the worsening of symptoms inherent to the condition during the premenstrual phase. Research consistently indicates that hormonal fluctuations during the menstrual cycle present a unique period of vulnerability for the onset or exacerbation of psychiatric symptoms, impacting diagnosis, risk assessment, and treatment. This review sought to elucidate the phenomenon of premenstrual exacerbation and its impact across a spectrum of psychiatric illnesses, including mood, anxiety, psychotic, obsessive-compulsive, personality, and trauma-related disorders. Despite the expanded research in recent years on premenstrual dysphoric disorder and premenstrual syndrome, premenstrual exacerbation remains underexplored and poorly defined. This review offers significant contributions to the diagnosis and management of psychiatric conditions, advocating for heightened awareness and novel treatment approaches in the context of premenstrual exacerbation.

摘要

现有精神障碍的经前加重是指在经前期病情固有的症状恶化。研究一致表明，月经周期中的激素波动为精神症状的发作或加重带来了一个独特的易损期，影响诊断、风险评估和治疗。本综述旨在阐明经前加重现象及其对一系列精神疾病的影响，包括情绪、焦虑、精神病性、强迫、人格和创伤相关障碍。尽管近年来对经前烦躁障碍和经前综合征的研究有所扩展，但经前加重仍未得到充分探索且定义不清。本综述对精神疾病的诊断和管理做出了重大贡献，倡导在经前加重的背景下提高认识并采用新的治疗方法。