Sandercock P, Molyneux A, Warlow C
Br Med J (Clin Res Ed). 1985 Jan 19;290(6463):193-7. doi: 10.1136/bmj.290.6463.193.
The usefulness of computed tomography (CT) was assessed in 325 consecutive patients with a "clinically definite first stroke" from a community stroke register. CT detected five "non-stroke" lesions (two cerebral gliomas, one cerebral metastasis, and two subdural haematomas), a frequency of 1.5%. Five patients were identified with cerebellar haemorrhage, but only one survived long enough to have a CT scan. CT was useful in excluding intracranial haemorrhage as the cause of the stroke in four patients receiving anticoagulants and seven receiving antiplatelet treatment; it showed intracranial haemorrhage in one patient taking aspirin. Forty six patients were in atrial fibrillation at the time of their stroke; four had intracranial haemorrhages and three had haemorrhagic cerebral infarcts. Nineteen patients with presumed ischaemic minor stroke were considered suitable for carotid endarterectomy; CT showed small haemorrhages in two. The CT scan provides very useful information in a minority (up to 28%) of patients with first stroke, who can be selected on quite simple criteria: (a) doubt (usually because of an inadequate history) whether the patient has stroke or a treatable intracranial lesion; (b) the possibility of cerebellar haemorrhage or infarction; (c) the exclusion of intracranial haemorrhage in patients who either are already taking or likely to need antihaemostatic drugs or are being considered for carotid endarterectomy; (d) if the patient deteriorates in a fashion atypical of stroke.
对社区卒中登记处连续纳入的325例“临床确诊首次卒中”患者进行了计算机断层扫描(CT)效用评估。CT检测出5例“非卒中”病变(2例脑胶质瘤、1例脑转移瘤和2例硬膜下血肿),频率为1.5%。5例患者被诊断为小脑出血,但只有1例存活时间足够长以进行CT扫描。CT有助于排除4例接受抗凝治疗和7例接受抗血小板治疗患者中脑出血作为卒中病因;在1例服用阿司匹林的患者中显示有颅内出血。46例患者在卒中时处于房颤状态;4例有颅内出血,3例有出血性脑梗死。19例推定的轻度缺血性卒中患者被认为适合行颈动脉内膜切除术;CT显示其中2例有小出血。CT扫描在少数(高达28%)首次卒中患者中提供了非常有用的信息,这些患者可根据相当简单的标准进行选择:(a)怀疑(通常由于病史不充分)患者是卒中还是可治疗的颅内病变;(b)存在小脑出血或梗死的可能性;(c)排除已经服用或可能需要抗止血药物或正在考虑行颈动脉内膜切除术患者的颅内出血;(d)如果患者以非典型卒中方式病情恶化。