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挥发性物质滥用导致的死亡:一项全国性流行病学研究。

Deaths from abuse of volatile substances: a national epidemiological study.

作者信息

Anderson H R, Macnair R S, Ramsey J D

出版信息

Br Med J (Clin Res Ed). 1985 Jan 26;290(6464):304-7. doi: 10.1136/bmj.290.6464.304.

Abstract

A survey of the United Kingdom detected 282 deaths from abuse of volatile substances during 1971-83. Deaths appeared to have increased in the most recent years, reaching 80 in 1983. Age at death ranged from 11 to 76 years but most deaths (72%) occurred under 20 years. Ninety five per cent of the subjects were male, and in 1983 deaths from volatile substance abuse accounted for 2% of all deaths in males aged 10-19. All areas of the United Kingdom were affected, the rates being highest in Scotland and urban areas. All social classes were affected, though rates were highest in social class V and the armed forces. The volatile substances abused were gas fuels (24%), mainly butane; aerosol sprays (17%); solvents in glues (27%); and other volatile substances, such as cleaning agents (31%). In 51% of cases death was attributed to the direct toxic effects of the substance abused, in 21% to plastic bag asphyxia, in 18% to inhalation of stomach contents, and in 11% to trauma. Deaths associated with the abuse of glues were more likely to be traumatic, but all substances appeared capable of killing directly by their toxic effects, probably by a cardiac mechanism. Only a small proportion of deaths (6%) were due to the abuse of glues among children under 16; hence current attempts to limit access of children to glues will probably have little impact on overall mortality.

摘要

一项对英国的调查发现,在1971年至1983年期间有282人死于挥发性物质滥用。近年来死亡人数似乎有所增加,1983年达到80人。死亡年龄在11岁至76岁之间,但大多数死亡(72%)发生在20岁以下。95%的死者为男性,1983年挥发性物质滥用导致的死亡占10至19岁男性所有死亡人数的2%。英国所有地区都受到影响,苏格兰和城市地区的死亡率最高。所有社会阶层都受到影响,尽管社会阶层V和武装部队的死亡率最高。滥用的挥发性物质包括气体燃料(24%),主要是丁烷;气溶胶喷雾(17%);胶水溶剂(27%);以及其他挥发性物质,如清洁剂(31%)。在51%的案例中,死亡归因于滥用物质的直接毒性作用,21%归因于塑料袋窒息,18%归因于吸入胃内容物,11%归因于创伤。与胶水滥用相关的死亡更可能是创伤性的,但所有物质似乎都能通过其毒性作用直接致死,可能是通过心脏机制。16岁以下儿童中因滥用胶水导致的死亡仅占一小部分(6%);因此,目前限制儿童接触胶水的措施可能对总体死亡率影响不大。

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