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在尼日利亚江户州一家教学医院就诊的高血压和糖尿病患者中,身体活动、肥胖与动脉粥样硬化性心血管疾病风险的关系。

Physical activity, obesity and risk of atherosclerotic cardiovascular diseases among patients with hypertension and diabetes attending a teaching hospital in Edo State, Nigeria.

机构信息

Department of Family Medicine, Edo State University, Uzairue, Nigeria.

Department of Internal Medicine, Irrua Specialist Teaching Hospital, Irrua, Nigeria.

出版信息

PLoS One. 2024 Aug 23;19(8):e0307526. doi: 10.1371/journal.pone.0307526. eCollection 2024.

Abstract

INTRODUCTION

Preventing Atherosclerotic Cardiovascular Diseases (ASCVD) can best be achieved by promoting a healthy lifestyle through improvements in diet, physical activity, and avoidance of tobacco use and exposure to second-hand smoke. The study aimed to determine the association between physical activity as well as obesity and the risk of atherosclerotic cardiovascular diseases among patients with hypertension and diabetes attending Irrua Specialist Teaching Hospital (ISTH), Irrua, Nigeria.

METHODOLOGY

The research was a descriptive, cross-sectional study of 394 systematically selected consenting patients with hypertension and diabetes presenting to a teaching hospital in Irrua, Edo State, Nigeria. The Cardiovascular risk assessment was determined using the Framingham 10year Risk of General Cardiovascular Disease. Anthropometric assessment, blood pressure and blood glucose were determined. Data was collected with a semi-structured questionnaire and analysed with Stata version 16. Chi square and logistic regression was used to test for association and significance level was set at p = 0.05.

RESULTS

The study included 394 participants with a mean age of 54±15.47years. Respondents were mostly females (55.3%), physically inactive (70.3%), overweight (42.4%) and had a high risk (41.8%) of developing CVD in 10 years using Framingham categorisation. There was a significant association between physical activity (P<0.01; OR 2.45; CI: 1.53-3.92), obesity (P<0.01; OR 2.52; CI: 1.64-3.86) and risk of developing CVD.

CONCLUSION

The study found a statistically significant relationship between physical inactivity, obesity, and the risk of atherosclerotic cardiovascular diseases. Increasing physical activity levels need to be a top priority at all levels of healthcare as well as the general population.

摘要

简介

预防动脉粥样硬化性心血管疾病(ASCVD)的最佳方法是通过改善饮食、增加身体活动、避免使用烟草和接触二手烟来促进健康的生活方式。本研究旨在确定身体活动以及肥胖与在尼日利亚伊鲁阿专科教学医院(ISTH)就诊的高血压和糖尿病患者发生动脉粥样硬化性心血管疾病风险之间的关系。

方法

这是一项在尼日利亚江户州伊鲁阿的一所教学医院就诊的高血压和糖尿病患者中进行的描述性、横断面研究。使用弗雷明汉 10 年一般心血管疾病风险评估心血管风险。进行人体测量评估、血压和血糖检测。使用半结构式问卷收集数据,并使用 Stata 版本 16 进行分析。卡方检验和逻辑回归用于检验相关性,显著性水平设为 p = 0.05。

结果

该研究纳入了 394 名参与者,平均年龄为 54±15.47 岁。受访者主要为女性(55.3%)、身体不活跃(70.3%)、超重(42.4%),且根据弗雷明汉分类,10 年内发生 CVD 的风险较高(41.8%)。身体活动(P<0.01;OR 2.45;CI:1.53-3.92)、肥胖(P<0.01;OR 2.52;CI:1.64-3.86)与发生 CVD 的风险之间存在显著关联。

结论

本研究发现身体活动不足、肥胖与动脉粥样硬化性心血管疾病风险之间存在统计学显著关系。增加身体活动水平应成为各级医疗保健以及普通人群的首要任务。

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