Consultant in Pediatric Dentistry, Department of Pediatric Dentistry and Orthodontic Sciences, College of Dentistry, King Khalid University, Abha, Saudi Arabia.
Department of Pediatric Dentistry and Orthodontic Sciences College of Dentistry, King Khalid University, Abha, Saudi Arabia.
Photobiomodul Photomed Laser Surg. 2024 Aug;42(8):550-560. doi: 10.1089/photob.2024.0070.
To evaluate hydroxyapatite-silver (HA-Ag) hybrid nanoparticles (NPs), as an antibacterial agent when integrated in self-etch (SE) adhesive. Blue light activated HA-Ag hybrid NP incorporation on mechanical properties, degree of conversion (DC), and microtensile bond strength (μTBS). Eighty primary molar teeth have carious lesions reaching the dentin but not involving the pulp. The infected dentin was removed and carious-affected dentin (CAD) was preserved. Forty samples were inoculated with . All primary teeth ( = 80) were allocated into four groups based on the incorporation of HA-Ag hybrid NPs in different concentrations (0%, 1%, 5%, and 10%). Group 1: 0% HA-Ag hybrid NPs + Clearfil SE bond primer, group 2: 1% HA-Ag hybrid NPs + Clearfil SE bond primer, group 3: 5 wt% HA-Ag NPs + Clearfil SE bond primer, and group 4: 10 wt% HA-Ag NPs + Clearfil SE bond primer. The survival rate assessment of was conducted on 40 inoculated samples. On the remaining primary teeth ( = 40), Clearfil SE bonding agent was applied uniformly via a blue light source. The composite buildup was performed on the samples and μTBS and failure analysis assessed. Fourier transform infrared spectroscopy was performed to assess DC. Survival rates of and μTBS among the tested groups were compared using ANOVA and Tukey post hoc analysis. 10 wt % HA-Ag NPs + Clearfil SE bond primer exhibited the highest level of antibacterial efficacy (0.14 ± 0.02 CFU/mL) against . The highest μTBS (18.38 ± 0.78 MPa) at the composite/CAD interface was in group 2 (1 wt % HA-Ag NPs + Clearfil SE bond primer + Clearfil SE bonding agent + activation with a blue light source). The highest DC was observed in the control group with Clearfil SE bond primer + Clearfil SE bonding agent + activation with a blue light source. 1 wt% HA-Ag hybrid NPs showed enhanced antibacterial effectiveness, DC, and bond strength of the SE adhesive to the primary CAD.
为评估羟基磷灰石-银（HA-Ag）杂化纳米颗粒（NPs）作为抗菌剂在自酸蚀（SE）胶粘剂中的应用，将其整合在其中。蓝光激活的 HA-Ag 杂化 NP 对力学性能、转化率（DC）和微拉伸粘结强度（μTBS）的影响。80 颗乳磨牙有龋损达牙本质但不涉及牙髓。去除感染的牙本质并保存龋损牙本质（CAD）。将 40 个样本接种。所有乳磨牙（n=80）根据不同浓度（0%、1%、5%和 10%）的 HA-Ag 杂化 NPs 的掺入情况分为四组。第 1 组：0%HA-Ag 杂化 NPs+Clearfil SE 粘结剂底漆，第 2 组：1%HA-Ag 杂化 NPs+Clearfil SE 粘结剂底漆，第 3 组：5wt%HA-Ag NPs+Clearfil SE 粘结剂底漆，第 4 组：10wt%HA-Ag NPs+Clearfil SE 粘结剂底漆。对 40 个接种样本进行了 的存活率评估。在剩余的 40 颗乳磨牙上，通过蓝光源均匀涂抹 Clearfil SE 粘结剂。在样本上进行复合堆积，并评估 μTBS 和失效分析。傅里叶变换红外光谱用于评估 DC。使用方差分析和 Tukey 事后分析比较测试组之间的 和 μTBS 存活率。10wt%HA-Ag NPs+Clearfil SE 粘结剂表现出最高的抗菌效果（0.14±0.02CFU/mL）针对 。复合/CAD 界面处最高的 μTBS（18.38±0.78MPa）在第 2 组（1wt%HA-Ag NPs+Clearfil SE 粘结剂底漆+Clearfil SE 粘结剂底漆+蓝光激活）中。对照组（Clearfil SE 粘结剂底漆+Clearfil SE 粘结剂底漆+蓝光激活）的 DC 最高。1wt%HA-Ag 杂化 NPs 显示出增强的抗菌效果、DC 和 SE 胶粘剂对原发性 CAD 的粘结强度。
