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老年急诊普通外科患者合并症和功能状态对结局的影响。

The impact of comorbidities and functional status on outcomes in the older adult emergency general surgery patient.

机构信息

Division of Trauma, Emergency Surgery, and Surgical Critical Care, Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.

Division of Trauma, Emergency Surgery, and Surgical Critical Care, Department of Surgery, Massachusetts General Hospital and Harvard Medical School, Boston, MA, United States.

出版信息

Am J Surg. 2024 Nov;237:115903. doi: 10.1016/j.amjsurg.2024.115903. Epub 2024 Aug 15.

Abstract

BACKGROUND

The aim of this study is to quantify the relative contribution of comorbidities and pre-operative functional status on outcomes in geriatric emergency general surgery (EGS) patients.

METHODS

This is a retrospective study of older-adult EGS patients at an academic medical center between 2017 and 2018. Patients ≥65 years were included. The primary outcomes examined were 30-day mortality, 30-day morbidity, and length of stay (LOS).

RESULTS

734 patients were included. The mean age was 76, and 48.9 ​% received non-operative management. The median LOS was 6.8 days; 11.8 ​% of patients died within 30 days, and 40.6 ​% developed morbidities. Lacking capacity to consent on admission was independently associated with 30-day mortality (OR: 2.63, [1.32-5.25], p ​= ​0.006). Comorbidities associated with developing morbidity were CVA with neurologic deficit (OR: 2.29, [1.20-4.36], p ​= ​0.012), CHF (OR: 2.60, [1.64-4.11], p ​< ​0.001), in addition to pre-operative delirium (OR: 3.42, [1.43-8.14], p ​= ​0.006).

CONCLUSIONS

A significant contribution to outcomes is determined by pre-admission comorbidities and cognitive and functional status. Opportunities exist for collaboration between Acute Care Surgery and geriatric medicine teams for the optimization of comorbidities.

摘要

背景

本研究旨在量化合并症和术前功能状态对老年急诊普通外科(EGS)患者结局的相对贡献。

方法

这是对 2017 年至 2018 年期间在学术医疗中心接受老年 EGS 治疗的患者进行的回顾性研究。纳入年龄≥65 岁的患者。主要观察指标为 30 天死亡率、30 天发病率和住院时间(LOS)。

结果

共纳入 734 例患者,平均年龄为 76 岁,48.9%接受了非手术治疗。中位 LOS 为 6.8 天;30 天内有 11.8%的患者死亡,40.6%的患者出现并发症。入院时无能力同意治疗与 30 天死亡率独立相关(OR:2.63,[1.32-5.25],p=0.006)。与发生并发症相关的合并症有伴有神经功能缺损的 CVA(OR:2.29,[1.20-4.36],p=0.012)、CHF(OR:2.60,[1.64-4.11],p<0.001),以及术前谵妄(OR:3.42,[1.43-8.14],p=0.006)。

结论

入院前的合并症以及认知和功能状态对结局有显著影响。急性外科和老年医学团队之间存在合作机会,以优化合并症的治疗。

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