Nomis Center for Immunobiology and Microbial Pathogenesis, Salk Cancer Center, Salk Institute for Biological Studies, La Jolla, CA, USA; School of Biological Sciences and Department of Radiation Medicine and Applied Sciences, University of California San Diego, La Jolla, CA, USA.
Cell. 2024 Aug 22;187(17):4551-4553. doi: 10.1016/j.cell.2024.07.037.
Two recent studies reveal that the extent of fitness or anergy in tumor-associated memory B cells is vital to anti-tumor immune response, cancer patient survival, and response to immune therapy. The impact of these seminal findings demonstrates the untapped potential for using B cells to combat the lethality of cancer.
最近的两项研究表明，肿瘤相关记忆 B 细胞的活跃程度对于抗肿瘤免疫反应、癌症患者的生存以及对免疫治疗的反应至关重要。这些开创性发现的影响表明，利用 B 细胞来对抗癌症的致命性具有巨大的潜力。
