Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, NC, USA.
Center for Biomolecular and Tissue Engineering, Duke University, Durham, NC, USA.
Nat Methods. 2024 Sep;21(9):1575-1577. doi: 10.1038/s41592-024-02393-5.
Biomaterials are revolutionizing organoid development by offering tunable platforms that provide instructive cues, which enhance cell fate transitions, tissue-level functions and reproducibility. These advances are crucial for harnessing the translational potential of organoids.
生物材料通过提供可调节的平台为类器官的发展带来了变革,这些平台提供了指导线索,增强了细胞命运的转变、组织水平的功能和重现性。这些进展对于挖掘类器官的转化潜力至关重要。