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释放生物材料的力量以增强类器官的分化和功能。

Unleashing the power of biomaterials to enhance organoid differentiation and function.

机构信息

Department of Biomedical Engineering, Pratt School of Engineering, Duke University, Durham, NC, USA.

Center for Biomolecular and Tissue Engineering, Duke University, Durham, NC, USA.

出版信息

Nat Methods. 2024 Sep;21(9):1575-1577. doi: 10.1038/s41592-024-02393-5.

DOI:10.1038/s41592-024-02393-5
PMID:39179910
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11479998/
Abstract

Biomaterials are revolutionizing organoid development by offering tunable platforms that provide instructive cues, which enhance cell fate transitions, tissue-level functions and reproducibility. These advances are crucial for harnessing the translational potential of organoids.

摘要

生物材料通过提供可调节的平台为类器官的发展带来了变革,这些平台提供了指导线索,增强了细胞命运的转变、组织水平的功能和重现性。这些进展对于挖掘类器官的转化潜力至关重要。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d3b/11479998/82ab75ee2f45/nihms-2025649-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d3b/11479998/82ab75ee2f45/nihms-2025649-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5d3b/11479998/82ab75ee2f45/nihms-2025649-f0001.jpg

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