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毒理学家的生物统计学与流行病学:似然比

Biostatistics and Epidemiology for the Toxicologist: Likelihood Ratios.

作者信息

Chan Gar Ming, Su Mark K

机构信息

Launceston General Hospital, Launceston, Tasmania, 7250, Australia.

Division of Medical Toxicology, Ronald O. Perelman, Department of Emergency Medicine, NYU Grossman, School of Medicine, 455 First Avenue, Room 124, New York, NY, 10016, USA.

出版信息

J Med Toxicol. 2024 Oct;20(4):411-415. doi: 10.1007/s13181-024-01026-9. Epub 2024 Aug 23.

Abstract

Likelihood ratios compare two values (i.e., case rates) in order to illustrate the magnitude of the difference between the two. This ratio increases the confidence one can have in a diagnostic test from a different vantage point than that of sensitivity and specificity. The calculations of likelihood ratios are presented along with a simplified approach. Likelihood ratios are another tool the toxicologist should employ in their understanding of statistics and probability.

摘要

似然比比较两个值(即病例率),以说明两者之间差异的大小。该比值从与灵敏度和特异度不同的角度提高了人们对诊断试验的信心。文中给出了似然比的计算方法以及一种简化方法。似然比是毒理学家在理解统计学和概率时应使用的另一种工具。

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