Food Safety Division, Department of Environmental Health Engineering, School of Public Health, Tehran University of Medical Sciences and Health Services, Tehran, Iran.
Department of Public Health, School of Health, Social Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand, Iran.
Sci Rep. 2024 Aug 24;14(1):19701. doi: 10.1038/s41598-024-70745-4.
Melamine is a recognized food contaminant that can arise incidentally or intentionally in specific categories of food. This study aimed to validate the melamine detection and quantification in infant formula and milk powders and also analyzed 40 samples consist of infant formula and milk powders from commercially available food products, from different geographic regions of Iran. The approximate content of melamine in samples was measured by High-performance liquid chromatography-ultra violet (HPLC-UV) system. A calibration curve (R = 0.9925) was established for detection of melamine in the range of 0.1-1.2 μg mL. Limit of quantification and limit of detection were 1 μg mL and 3 μg mL, respectively. The presence of melamine in infant formula and milk powdered was investigated and it was observed that the amount of melamine in samples of infant formulas and milk powders was 0.001-0.095 mg kg and 0.001-0.004 mg kg, respectively. These values were found to be within the prescribed limits by the European Union and Codex Alimentarius Commission legislation. It is important to note that the consumption of these dairy products, which contain low content of melamine, does not pose any significant threat to consumer health. Furthermore, the results of the risk assessment confirmed this issue.
三聚氰胺是一种公认的食品污染物，可能在某些特定类别食品中偶然或故意出现。本研究旨在验证婴幼儿配方奶粉和乳粉中三聚氰胺的检测和定量分析方法，并对来自伊朗不同地理区域的商业销售食品中的 40 个婴幼儿配方奶粉和乳粉样本进行了分析。采用高效液相色谱-紫外（HPLC-UV）系统测定样品中三聚氰胺的近似含量。建立了三聚氰胺在 0.1-1.2μg mL 范围内的检测校准曲线（R=0.9925）。定量限和检测限分别为 1μg mL 和 3μg mL。研究了婴幼儿配方奶粉和乳粉中三聚氰胺的存在情况，结果表明，婴幼儿配方奶粉和乳粉中三聚氰胺的含量分别为 0.001-0.095mg/kg 和 0.001-0.004mg/kg，均在欧盟和食品法典委员会法规规定的允许范围内。需要注意的是，这些乳制品的摄入量较低，不会对消费者健康构成任何重大威胁。此外，风险评估的结果也证实了这一点。
