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接受造口术的全髋关节置换患者发生假体周围关节感染翻修的风险增加,但全膝关节置换患者则不然。

Total Hip Arthroplasty Patients Who Have Ostomies Have an Increased Risk of Revisions for Periprosthetic Joint Infection, but Total Knee Arthroplasty Patients Do Not.

作者信息

Habibi Akram A, Kingery Matthew T, Anil Utkarsh, Lin Charles C, Schwarzkopf Ran, Davidovitch Roy I

机构信息

Department of Orthopedic Surgery, NYU Langone Health, New York, New York.

出版信息

J Arthroplasty. 2025 Feb;40(2):352-358.e8. doi: 10.1016/j.arth.2024.08.031. Epub 2024 Sep 7.

Abstract

BACKGROUND

Patient comorbidities can lead to worse outcomes and increase the risk of revisions after total hip arthroplasty (THA) and total knee arthroplasty (TKA). Sparse research is available on the effects of ostomies on postoperative outcomes. Our study aimed to assess whether patients who have ostomies, who underwent TKA or THA, have worse outcomes and increased rates of all-cause and periprosthetic joint infection (PJI)-related revisions.

METHODS

We performed a retrospective cohort study comparing the outcomes of THA and TKA patients who have and do not have a history of ostomy using the Statewide Planning and Research Cooperative System. Patient demographics, ostomy diagnosis, 3-month emergency department visits and readmissions, and revisions were collected. A total of 126,414 THA and 216,037 TKA cases were included. Log-rank testing and a Cox proportional hazards model were used to account for covariates.

RESULTS

In total, 463 THA patients (0.4%) had ostomies. They had a longer length of stay (4.0 versus 3.1 days, P < 0.001) and were less likely to be discharged home (55.3 versus 62.2%, P = 0.01). They had higher rates of PJI-related revisions (1.9 versus 0.9%, P = 0.02) and had increased odds of PJI-related revision (OR [odds ratio] = 2.2, P = 0.02). Of TKA patients, 619 patients (0.3%) had an ostomy. They had a longer length of stay (3.6 versus 3.3 days, P = 0.02) and was less likely to be discharged home (49.4 versus 52.4%, P = 0.16). However, there was no difference in the rate (1.8 versus 1.4%, P = 0.49) or odds (OR = 1.2, P = 0.53) of PJI-related revision.

CONCLUSIONS

THA, but not TKA, patients who have ostomies have an increased risk of PJI-related revisions. The proximity of the surgical incision to the ostomy site may play a role in the risk of PJI in THA patients.

摘要

背景

患者的合并症可能导致全髋关节置换术(THA)和全膝关节置换术(TKA)后出现更差的结果,并增加翻修风险。关于造口术对术后结果影响的研究较少。我们的研究旨在评估接受TKA或THA的造口术患者是否有更差的结果以及全因和假体周围关节感染(PJI)相关翻修率是否增加。

方法

我们使用全州规划与研究合作系统进行了一项回顾性队列研究,比较有和没有造口术病史的THA和TKA患者的结果。收集患者人口统计学资料、造口术诊断、3个月内的急诊科就诊和再入院情况以及翻修情况。共纳入126414例THA病例和216037例TKA病例。使用对数秩检验和Cox比例风险模型来考虑协变量。

结果

总共有463例THA患者(0.4%)有造口术。他们的住院时间更长(4.0天对3.1天,P<0.001),出院回家的可能性更小(55.3%对62.2%,P=0.01)。他们的PJI相关翻修率更高(1.9%对0.9%,P=0.02),PJI相关翻修的几率增加(比值比[OR]=2.2,P=0.02)。在TKA患者中,619例患者(0.3%)有造口术。他们的住院时间更长(3.6天对3.3天,P=0.02),出院回家的可能性更小(49.4%对52.4%,P=0.16)。然而,PJI相关翻修的发生率(1.8%对1.4%)或几率(OR=1.2,P=0.53)没有差异。

结论

有造口术的THA患者而非TKA患者,PJI相关翻修的风险增加。手术切口与造口部位的接近程度可能在THA患者发生PJI的风险中起作用。

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