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A study of ultralow dose rituximab as adjuvant to standard of care in treatment of significant and extensive pemphigus vulgaris: A case series.

作者信息

Patel Nayankumar H, Padhiyar Jignaben K, Patel Jahnvi R, Patel Kathak A, Lakum Megha P, Oza Yaksh Pradeep, Patel Harisiddhi Bharatbhai, Chaudhary Prashant Bhikhabhai

机构信息

Department of Skin and VD, GCS Medical College, Hospital and Research Centre, Ahmedabad, Gujarat.

Department of Skin and VD, GCS Medical College, Hospital and Research Centre, Ahmedabad, Gujarat.

出版信息

J Am Acad Dermatol. 2024 Dec;91(6):1243-1245. doi: 10.1016/j.jaad.2024.07.1506. Epub 2024 Sep 7.

DOI:10.1016/j.jaad.2024.07.1506
PMID:39182691
Abstract
摘要

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1
A study of ultralow dose rituximab as adjuvant to standard of care in treatment of significant and extensive pemphigus vulgaris: A case series.一项关于超低剂量利妥昔单抗作为标准治疗辅助药物治疗重度广泛性寻常型天疱疮的病例系列研究。
J Am Acad Dermatol. 2024 Dec;91(6):1243-1245. doi: 10.1016/j.jaad.2024.07.1506. Epub 2024 Sep 7.
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Role of Rituximab in the Treatment of Pemphigus Vulgaris: Patient Selection and Acceptability.利妥昔单抗在寻常型天疱疮治疗中的作用:患者选择与可接受性
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Ultra-low dose rituximab for refractory pemghigus vulgaris: a pilot study.超低保额利妥昔单抗治疗难治性寻常型天疱疮:一项初步研究。
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Is It Time to Reconsider Rituximab Dosing Regimens for Pemphigus Vulgaris?是时候重新考虑寻常型天疱疮的利妥昔单抗给药方案了吗?
Antibodies (Basel). 2024 Jan 5;13(1):4. doi: 10.3390/antib13010004.
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Persistent B Lymphocyte Depletion After an Ultralow Dose of Rituximab for Pemphigus Vulgaris.超低剂量利妥昔单抗治疗寻常型天疱疮后B淋巴细胞持续耗竭
J Investig Allergol Clin Immunol. 2018 Oct;28(5):347-348. doi: 10.18176/jiaci.0283.
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Comparison of rituximab and conventional adjuvant therapy for pemphigus vulgaris: A retrospective analysis.比较寻常型天疱疮利妥昔单抗与传统辅助治疗:回顾性分析。
PLoS One. 2018 Sep 25;13(9):e0198074. doi: 10.1371/journal.pone.0198074. eCollection 2018.
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Rituximab is an effective treatment in patients with pemphigus vulgaris and demonstrates a steroid-sparing effect.利妥昔单抗对寻常型天疱疮患者是一种有效的治疗方法,并具有激素节省作用。
Br J Dermatol. 2020 May;182(5):1111-1119. doi: 10.1111/bjd.18482. Epub 2019 Nov 28.
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SARS-CoV-2 Infection in Pemphigus Vulgaris Two Weeks after Rituximab Therapy with Total Recovery: A Case Report.天疱疮患者利妥昔单抗治疗 2 周后发生 SARS-CoV-2 感染并完全康复:1 例病例报告。
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Dermatologic rituximab dosing: treatment of refractory pemphigus vulgaris in an adolescent male.皮肤科利妥昔单抗给药:一名青少年男性难治性寻常型天疱疮的治疗
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Prolonged treatment with rituximab in patients with refractory pemphigus vulgaris.利妥昔单抗对难治性寻常型天疱疮患者的长期治疗。
J Dermatolog Treat. 2007;18(5):312-4. doi: 10.1080/09546630701323988.

引用本文的文献

1
Efficacy and safety of low dose rituximab in pemphigus: an updated systematic review and meta-analysis.低剂量利妥昔单抗治疗天疱疮的疗效和安全性:一项更新的系统评价和荟萃分析
Front Immunol. 2025 Jul 25;16:1605243. doi: 10.3389/fimmu.2025.1605243. eCollection 2025.
2
Ultra-Low-Dose Rituximab in Pemphigus Vulgaris: How Low is the Lowest?超低剂量利妥昔单抗治疗寻常型天疱疮:最低剂量能有多低?
Indian Dermatol Online J. 2025 Jun 10;16(4):704-705. doi: 10.4103/idoj.idoj_1266_24. eCollection 2025 Jul-Aug.
3
Rituximab in Pemphigus - Exploring the Less Frequently Travelled Terrains.
利妥昔单抗治疗天疱疮——探索较少涉足的领域
Indian Dermatol Online J. 2025 Jun 27;16(4):537-538. doi: 10.4103/idoj.idoj_649_25. eCollection 2025 Jul-Aug.