State Key Laboratory of Food Nutrition and Safety, College of Food Science and Engineering, Tianjin Key Laboratory of Food Quality and Health, Tianjin University of Science and Technology, Tianjin 300457, PR China.
School of Integrative Medicine, Tianjin University of Traditional Chinese Medicine, Tianjin 301617, PR China.
Int J Biol Macromol. 2024 Oct;278(Pt 4):135047. doi: 10.1016/j.ijbiomac.2024.135047. Epub 2024 Aug 23.
An advanced biodegradable packaging film with antimicrobial and fresh-maintaining functions was constructed by incorporating berberine and L-arginine into the starch/polyvinyl alcohol (PVA) film matrix. The film was endowed with a dual antibacterial capacity thanks to the intrinsic antibacterial capability of berberine and cascaded photodynamic sterilization. The aggregated berberine presents an excellent photodynamic activity to generate reactive oxygen species (ROS), which further triggers the NO release from L-arginine. Under the synergetic action of ROS and NO, the as-prepared film not only has an antibacterial efficiency of over 99 % against both S. aureus and E. coli but also delays fruit ripening through antagonistic effects on ethylene to extend the shelf life of food. Meanwhile, the as-prepared film presents UV-shielding properties, thermal stability, and considerable mechanical properties. Specifically, the packaging film exhibits good biocompatibility and is biodegradable, with a degradation rate of 56 % within 16 days, which has great potential for improving food safety and environmental events.
构建了一种具有抗菌和保鲜功能的先进可生物降解包装膜，方法是将小檗碱和 L-精氨酸掺入淀粉/聚乙烯醇（PVA）膜基质中。由于小檗碱的固有抗菌能力和级联光动力杀菌作用，该膜具有双重抗菌能力。聚集的小檗碱呈现出优异的光动力活性，可产生活性氧（ROS），进而触发 L-精氨酸释放一氧化氮（NO）。在 ROS 和 NO 的协同作用下，所制备的薄膜不仅对金黄色葡萄球菌和大肠杆菌的抗菌效率超过 99%，而且还通过拮抗乙烯来延缓水果成熟，从而延长食品的保质期。同时，所制备的薄膜具有遮光性、热稳定性和相当好的机械性能。具体而言，包装膜具有良好的生物相容性和可生物降解性，在 16 天内降解率为 56%，在提高食品安全和应对环境事件方面具有巨大潜力。
