Jasrotia Sakshi, Gupta Sonali, Kudipady Manas Laxman, Puttaiahgowda Yashoda Malgar
Department of Chemistry, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Department of Information and Communication Technology, Manipal Institute of Technology, Manipal Academy of Higher Education, Manipal, Karnataka, 576104, India.
Curr Res Food Sci. 2025 Aug 9;11:101159. doi: 10.1016/j.crfs.2025.101159. eCollection 2025.
The global food waste crisis, driven by rapid spoilage and oxidative degradation, substantiates the urgent need for sustainable packaging innovations. Though mechanically robust, conventional petroleum-based polymers contribute significantly to environmental pollution due to their non-biodegradability. Quercetin (Qr), a bioactive flavonoid with potent antimicrobial and antioxidant properties, has emerged as a promising component in next-generation active packaging. This review examines Qr-functionalized nanocomposite films, focusing on their ability to inhibit pathogens (e.g., ) and prevent oxidative damage through radical scavenging and metal chelation. Advanced fabrication methods like solution casting and electrospinning enhance Qr's controlled release, mechanical strength, and UV-shielding capabilities. The synergistic use of biopolymers (e.g., CS, PVA) and nanofillers (e.g., ZnO, Ag NPs) further enhances thermal stability, biodegradability, and antimicrobial performance. Studies show that Qr-based films can extend food shelf life by up to 50 %, significantly reducing microbial loads and oxidative markers. Despite its GRAS status, challenges like production scalability, cost-effectiveness, and long-term stability remain. By integrating nanotechnology with bioactive compounds like Qr, this innovation represents a paradigm shift toward intelligent, eco-friendly packaging aligned with the United Nations Sustainable Development Goals (SDGs).
由快速变质和氧化降解驱动的全球食品浪费危机，凸显了对可持续包装创新的迫切需求。传统的石油基聚合物虽然机械性能强劲，但由于其不可生物降解性，对环境污染有很大影响。槲皮素（Qr）是一种具有强大抗菌和抗氧化特性的生物活性黄酮类化合物，已成为下一代活性包装中一种很有前景的成分。本综述研究了Qr功能化纳米复合薄膜，重点关注其抑制病原体（如 ）以及通过自由基清除和金属螯合防止氧化损伤的能力。溶液浇铸和静电纺丝等先进制造方法提高了Qr的控释、机械强度和紫外线屏蔽能力。生物聚合物（如CS、PVA）和纳米填料（如ZnO、Ag NPs）的协同使用进一步提高了热稳定性、生物降解性和抗菌性能。研究表明，基于Qr的薄膜可将食品保质期延长多达50%，显著降低微生物负荷和氧化指标。尽管其具有公认安全（GRAS）地位，但生产可扩展性、成本效益和长期稳定性等挑战依然存在。通过将纳米技术与Qr等生物活性化合物相结合，这一创新代表了朝着符合联合国可持续发展目标（SDGs）的智能、环保包装的范式转变。
