Liu Ting, Ma Chunfeng, Hu Zheng, Huang Yinghong, Wang Xian
Key Laboratory of Analytical Chemistry of the State Ethnic Affairs Commission, School of Chemistry and Materials Science, South-Central Minzu University, Wuhan, Hubei, 430074, China.
Key Laboratory of Analytical Chemistry of the State Ethnic Affairs Commission, School of Chemistry and Materials Science, South-Central Minzu University, Wuhan, Hubei, 430074, China.
Anal Chim Acta. 2024 Sep 22;1323:343067. doi: 10.1016/j.aca.2024.343067. Epub 2024 Aug 6.
Perfluorinated compounds (PFCs) are a class of widely manufactured and used emerging persistent pollutants. The recent discovered new class of macrocycles pillararenes have garnered significant attention for the applications in environmental pollutant adsorption, with abundant π electron cavities, a symmetrical rigid structure, and host-guest recognition capabilities.
In this work, we designed and synthesized novel cationic pillar [n]arenes magnetic nanoparticles (CWPA5@MNPs), and investigated its adsorption performance and mechanism as a type of new adsorbent for the enrichment of PFCs. The results indicate that CWPA5@MNPs exhibits selectively strong affinity for perfluorooctane sulfonate (PFOS) and long-chain (C-C) perfluorocarboxylic acids (PFCAs), with the adsorption efficiency exceeding 80 % within 12 min. The maximum adsorption capacity of CWPA5@MNPs for PFOS was measured to be 29.02 mg/g. CWPA5@MNPs can be rapidly isolated from the solution using external magnets, offering a quick and easy separation. Consequently, this study established a CWPA5@MNPs-assisted magnetic solid-phase extraction (MSPE) coupled with high-performance liquid chromatography-tandem mass spectrometry (CWPA5@MNPs-MSPE-HPLC-MS/MS) method for the rapid detection of trace levels of PFCs in environmental water samples. The analysis of 7 PFCs yielded recovery rates ranging from 86.1 % to 107.5 %, with intraday and interday relative standard deviations (RSD) of 3.6-6.4 % and 1.3-7.0 %, respectively.
The study reveals the synthesis and application of novel cationic pillar [n]arenes magnetic nanoparticles (CWPA5@MNPs) as highly efficient adsorbents for selective perfluorinated compounds (PFCs) in water samples. It demonstrates the potential of the newly developed CWPA5@MNPs-MSPE-HPLC-MS/MS method for the quantitative analysis of PFCs in environment, with high sensitivity, accuracy and stability.
全氟化合物（PFCs）是一类广泛生产和使用的新兴持久性污染物。最近发现的新型大环化合物柱芳烃因其在环境污染物吸附方面的应用而备受关注，它具有丰富的π电子空腔、对称的刚性结构以及主客体识别能力。
在本研究中，我们设计并合成了新型阳离子柱[n]芳烃磁性纳米颗粒（CWPA5@MNPs），并研究了其作为一种新型吸附剂对全氟化合物进行富集的吸附性能及机制。结果表明，CWPA5@MNPs对全氟辛烷磺酸（PFOS）和长链（C-C）全氟羧酸（PFCAs）表现出选择性强亲和力，在12分钟内吸附效率超过80%。测得CWPA5@MNPs对PFOS的最大吸附容量为29.02 mg/g。CWPA5@MNPs可利用外部磁铁从溶液中快速分离，实现快速简便的分离。因此，本研究建立了一种CWPA5@MNPs辅助的磁性固相萃取（MSPE）结合高效液相色谱-串联质谱（CWPA5@MNPs-MSPE-HPLC-MS/MS）方法，用于快速检测环境水样中痕量的全氟化合物。对7种全氟化合物的分析回收率在86.1%至107.5%之间，日内和日间相对标准偏差（RSD）分别为3.6 - 6.4%和1.3 - 7.0%。
该研究揭示了新型阳离子柱[n]芳烃磁性纳米颗粒（CWPA5@MNPs）作为水样中选择性全氟化合物（PFCs）高效吸附剂的合成与应用。证明了新开发的CWPA5@MNPs-MSPE-HPLC-MS/MS方法在环境中全氟化合物定量分析方面具有高灵敏度、准确性和稳定性的潜力。
