Shaping smell: chloride currents dictate the kinetics of olfactory transduction.
作者信息
Fyke Zach, Belonio Kai Clane, Zak Joseph D
机构信息
Department of Biological Sciences, University of Illinois Chicago, Chicago, Illinois, USA.
Graduate Program in Neuroscience, University of Illinois Chicago, Chicago, Illinois, USA.
出版信息
J Physiol. 2024 Oct;602(19):4699-4700. doi: 10.1113/JP287393. Epub 2024 Aug 26.
Abstract
摘要
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Calcium-activated chloride channels clamp odor-evoked spike activity in olfactory receptor neurons.钙激活氯离子通道钳制嗅觉受体神经元中气味诱发的尖峰活动。
Sci Rep. 2018 Jul 13;8(1):10600. doi: 10.1038/s41598-018-28855-3.
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Ca-activated Cl current predominates in threshold response of mouse olfactory receptor neurons.钙激活氯离子电流在小鼠嗅觉受体神经元的阈反应中占主导地位。
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The Ca2+-activated Cl- channel TMEM16B regulates action potential firing and axonal targeting in olfactory sensory neurons.钙离子激活的氯离子通道TMEM16B调节嗅觉感觉神经元的动作电位发放和轴突靶向。
J Gen Physiol. 2016 Oct;148(4):293-311. doi: 10.1085/jgp.201611622. Epub 2016 Sep 12.
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Nonlinear amplification by calcium-dependent chloride channels in olfactory receptor cells.嗅觉受体细胞中钙依赖性氯离子通道介导的非线性放大作用。
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