Zhao Haiyuan, Liu Gang, Li Yang, Lu Feixiang, Yang Nianzhao, Zhao Jun
Department of General Surgery, The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College), Wuhu, China.
Front Nutr. 2024 Aug 9;11:1398807. doi: 10.3389/fnut.2024.1398807. eCollection 2024.
The present study aimed to evaluate the association between body fat ratio (BFR), visceral fat area (VFA), body mass index (BMI) and visceral fat density (VFD) and assess their reliability in assessing risk of postoperative complications and survival status in patients with rectal cancer (RC).
The present study retrospectively included 460 patients who underwent surgical treatment for RC at the First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College, Wuhu, China) between September 2018 and July 2021. BFR, VFA, BMI, and VFD were measured and basic information, clinical data, complications and survival were recorded.
Statistical analysis was performed to determine optimal BFR cut-off and evaluate group differences. BFR demonstrated a significant positive correlation with VFA ( = 0.739) and BMI ( = 0.783) and significant negative correlation with VFD ( = -0.773). The areas under the receiver operating characteristic curve of BFR, VFA, BMI, and VFD in predicting postoperative complications in RC were all >0.7 and the optimal cut-off value of BFR was 24.3. Patients in the BFR-low group had fewer postoperative complications, lower intraoperative indices, shorter hospitalization times and lower costs than those in the BFR-high group. BFR predicted complications with high diagnostic significance and was validated by multiple models. Furthermore, patients in the BFR-high group had a longer overall survival compared with patients in the BFR-low group.
BFR was associated with BMI, VFA, and VFD. A BFR threshold of 24.3 was correlated with decreased complications and enhanced long-term survival.
本研究旨在评估体脂率（BFR）、内脏脂肪面积（VFA）、体重指数（BMI）和内脏脂肪密度（VFD）之间的关联，并评估它们在评估直肠癌（RC）患者术后并发症风险和生存状况方面的可靠性。
本研究回顾性纳入了2018年9月至2021年7月期间在皖南医学院第一附属医院（皖南医学院弋矶山医院，中国芜湖）接受RC手术治疗的460例患者。测量了BFR、VFA、BMI和VFD，并记录了基本信息、临床数据、并发症和生存情况。
进行统计分析以确定最佳BFR临界值并评估组间差异。BFR与VFA（=0.739）和BMI（=0.783）呈显著正相关，与VFD（= -0.773）呈显著负相关。BFR、VFA、BMI和VFD预测RC术后并发症的受试者工作特征曲线下面积均>0.7，BFR的最佳临界值为24.3。BFR低组患者的术后并发症少于BFR高组，术中指标更低住院时间更短且费用更低。BFR对并发症具有较高的诊断意义，并经多种模型验证。此外，BFR高组患者的总生存期长于BFR低组患者。
BFR与BMI、VFA和VFD相关。24.3的BFR阈值与并发症减少和长期生存改善相关。
