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机器学习与深度学习助力改善直肠癌手术后吻合口漏的预防

Machine learning and deep learning to improve prevention of anastomotic leak after rectal cancer surgery.

作者信息

Celotto Francesco, Bao Quoc R, Capelli Giulia, Spolverato Gaya, Gumbs Andrew A

机构信息

Department of Surgical, Oncological and Gastroenterological Sciences, University of Padova, Padova 35128, Veneto, Italy.

Department of Surgery, Azienda Socio Sanitaria Territoriale Bergamo Est, Bergamo 24068, Lombardy, Italy.

出版信息

World J Gastrointest Surg. 2025 Jan 27;17(1):101772. doi: 10.4240/wjgs.v17.i1.101772.

DOI:10.4240/wjgs.v17.i1.101772
PMID:39872776
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11757192/
Abstract

Anastomotic leakage (AL) is a significant complication following rectal cancer surgery, adversely affecting both quality of life and oncological outcomes. Recent advancements in artificial intelligence (AI), particularly machine learning and deep learning, offer promising avenues for predicting and preventing AL. These technologies can analyze extensive clinical datasets to identify preoperative and perioperative risk factors such as malnutrition, body composition, and radiological features. AI-based models have demonstrated superior predictive power compared to traditional statistical methods, potentially guiding clinical decision-making and improving patient outcomes. Additionally, AI can provide surgeons with intraoperative feedback on blood supply and anatomical dissection planes, minimizing the risk of intraoperative complications and reducing the likelihood of AL development.

摘要

吻合口漏(AL)是直肠癌手术后的一种严重并发症,对生活质量和肿瘤学结局均产生不利影响。人工智能(AI)的最新进展,尤其是机器学习和深度学习,为预测和预防AL提供了有前景的途径。这些技术可以分析大量临床数据集,以识别术前和围手术期的风险因素,如营养不良、身体成分和放射学特征。与传统统计方法相比,基于AI的模型已显示出卓越的预测能力,有可能指导临床决策并改善患者结局。此外,AI可以为外科医生提供有关血供和解剖分离平面的术中反馈,将术中并发症的风险降至最低,并降低发生AL的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2804/11757192/925eba63c7d7/101772-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2804/11757192/925eba63c7d7/101772-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2804/11757192/925eba63c7d7/101772-g001.jpg

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本文引用的文献

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Serum nutritional predictive biomarkers and risk assessment for anastomotic leakage after laparoscopic surgery in rectal cancer patients.直肠癌患者腹腔镜手术后吻合口漏的血清营养预测生物标志物及风险评估
World J Gastrointest Surg. 2024 Oct 27;16(10):3142-3154. doi: 10.4240/wjgs.v16.i10.3142.
2
Body fat ratio as a novel predictor of complications and survival after rectal cancer surgery.体脂率作为直肠癌手术后并发症和生存的新型预测指标。
Front Nutr. 2024 Aug 9;11:1398807. doi: 10.3389/fnut.2024.1398807. eCollection 2024.
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Quantitative fluorescence angiography versus hyperspectral imaging to assess bowel ischemia: What is the best choice?
定量荧光血管造影与高光谱成像评估肠道缺血:最佳选择是什么?
Surgery. 2024 Nov;176(5):1550-1551. doi: 10.1016/j.surg.2024.06.030. Epub 2024 Jul 15.
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Early Postoperative Prediction of Complications and Readmission After Colorectal Cancer Surgery Using an Artificial Neural Network.基于人工神经网络的结直肠癌术后并发症和再入院的早期预测。
Dis Colon Rectum. 2024 Oct 1;67(10):1341-1352. doi: 10.1097/DCR.0000000000003253. Epub 2024 Jul 3.
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Laparoscopic Colorectal Surgery with Anatomical Recognition with Artificial Intelligence Assistance for Nerves and Dissection Layers.腹腔镜下结直肠手术中人工智能辅助的神经和解剖层面识别。
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Predicting multiple linear stapler firings in double stapling technique with an MRI-based deep-learning model.基于 MRI 的深度学习模型预测双吻合器技术中的多次线性吻合器击发。
Sci Rep. 2023 Nov 2;13(1):18906. doi: 10.1038/s41598-023-46225-6.
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Artificial intelligence based system for predicting permanent stoma after sphincter saving operations.基于人工智能的系统,用于预测保肛手术后的永久性造口。
Sci Rep. 2023 Sep 25;13(1):16039. doi: 10.1038/s41598-023-43211-w.
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Impact of anastomotic leakage on long-term prognosis after colorectal cancer surgery.吻合口漏对结直肠癌手术后长期预后的影响。
World J Gastrointest Surg. 2023 May 27;15(5):745-756. doi: 10.4240/wjgs.v15.i5.745.
9
Blood Perfusion Assessment by Indocyanine Green Fluorescence Imaging for Minimally Invasive Rectal Cancer Surgery (EssentiAL trial): A Randomized Clinical Trial.吲哚菁绿荧光成像引导的微创直肠癌手术中的血流灌注评估(EssentiAL 试验):一项随机临床试验。
Ann Surg. 2023 Oct 1;278(4):e688-e694. doi: 10.1097/SLA.0000000000005907. Epub 2023 May 23.
10
Applying interpretable machine learning algorithms to predict risk factors for permanent stoma in patients after TME.应用可解释的机器学习算法预测全直肠系膜切除术后患者永久性造口的危险因素。
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