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从整体角度看心肌恢复:心力衰竭亚专科优化患者治疗的哲学转变

Myocardial Recovery in the Systemic Context: A Philosophic Shift for the Heart Failure Subspecialty to Optimize Patient Care.

机构信息

Icahn School of Medicine at Mount Sinai, New York, New York, US.

Icahn School of Medicine at Mount Sinai, Mount Sinai Fuster Heart Hospital, The Mount Sinai Hospital, New York, New York, US.

出版信息

Methodist Debakey Cardiovasc J. 2024 Aug 20;20(4):98-108. doi: 10.14797/mdcvj.1416. eCollection 2024.

DOI:10.14797/mdcvj.1416
PMID:39184157
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11342849/
Abstract

Heart failure poses a significant challenge to healthcare systems and society at large, mainly due to its increasing prevalence among the aging population and its association with frequent hospitalizations with high mortality rates. At its core, heart failure management seeks to emphasize myocardial recovery across the spectrum of disease, from acute cardiogenic shock to ambulatory heart failure, with care ranging from consideration of mechanical circulatory support to medication optimization. In this review, we propose a definition of "recovery" that extends beyond the restoration of normal myocardial dynamics to the entire human organism, ultimately improving functional capacity and clinical outcomes. Prioritizing this more holistic definition of "recovery" allows a broader representation of the spectrum of disease and corresponding management that falls under the "heart failure" umbrella. In so doing, a more synchronized delivery of care across settings and disciplines may be feasible for the modern patient living with heart failure.

摘要

心力衰竭给医疗系统和整个社会带来了重大挑战,主要是因为其在老年人口中的发病率不断上升,以及与频繁住院和高死亡率相关。心力衰竭的管理核心在于强调心肌在从急性心源性休克到门诊心力衰竭等疾病谱中的恢复,从考虑机械循环支持到优化药物治疗,涵盖了从发病到治疗的各个阶段。在这篇综述中,我们提出了一个“恢复”的定义,它不仅限于恢复正常心肌动力学,而是延伸到整个人体,最终提高功能能力和临床结局。优先考虑这种更全面的“恢复”定义,可以更广泛地代表“心力衰竭”涵盖的疾病谱及其相应的管理。这样,在现代心力衰竭患者的治疗中,不同医疗机构和学科之间的治疗方案就可以更加协调一致。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d249/11342849/e20d9271d8d0/mdcvj-20-4-1416-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d249/11342849/9fe58668d680/mdcvj-20-4-1416-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d249/11342849/c993b40f3492/mdcvj-20-4-1416-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d249/11342849/e20d9271d8d0/mdcvj-20-4-1416-g3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d249/11342849/9fe58668d680/mdcvj-20-4-1416-g1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d249/11342849/c993b40f3492/mdcvj-20-4-1416-g2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d249/11342849/e20d9271d8d0/mdcvj-20-4-1416-g3.jpg

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本文引用的文献

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Reversals in the Decline of Heart Failure Mortality in the US, 1999 to 2021.1999年至2021年美国心力衰竭死亡率下降趋势的逆转
JAMA Cardiol. 2024 Jun 1;9(6):585-589. doi: 10.1001/jamacardio.2024.0615.
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SGLT2 Inhibitors, Functional Capacity, and Quality of Life in Patients With Heart Failure: A Systematic Review and Meta-Analysis.SGLT2 抑制剂在心力衰竭患者中的功能能力和生活质量:系统评价和荟萃分析。
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#WordsMatter: Supporting the Rebranding of "Palliative care" to "Supportive Cardiology" for Patients Living with Heart Failure.# 用词至关重要:支持将“姑息治疗”重新命名为“心力衰竭患者支持性心脏病学” 。
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Telemonitoring for heart failure: a meta-analysis.远程心力衰竭监测:一项荟萃分析。
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Association Between Sacubitril/Valsartan Initiation and Mitral Regurgitation Severity in Heart Failure With Reduced Ejection Fraction: The PROVE-HF Study.沙库巴曲缬沙坦起始治疗与射血分数降低的心力衰竭患者二尖瓣反流严重程度之间的关联:PROVE-HF研究
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Quality of life in patients with heart failure and improved ejection fraction: one-year changes and prognosis.射血分数改善的心力衰竭患者的生活质量:一年变化和预后。
ESC Heart Fail. 2022 Dec;9(6):3804-3813. doi: 10.1002/ehf2.14098. Epub 2022 Aug 2.
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Effectiveness of Family-Centered Empowerment Model on Psychological Improvement of Patients With Myocardial Infarction: A Bayesian Multivariate Approach.家庭为中心的赋能模式对心肌梗死患者心理改善的效果:贝叶斯多变量分析。
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Clinical myocardial recovery in advanced heart failure with long term left ventricular assist device support.长期左心室辅助装置支持下晚期心力衰竭的临床心肌恢复。
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