多重用药、意外后果及生活方式医学的影响
Polypharmacy, Unintended Consequences, and Impact of Lifestyle Medicine.
作者信息
Srivastava Sneha Baxi
机构信息
Rosalind Franklin University of Medicine and Science, North Chicago, IL, USA (SBS).
Lake County Health Department, Highland Park, IL, USA (SBS).
出版信息
Am J Lifestyle Med. 2023 Oct 26;18(1):54-57. doi: 10.1177/15598276231207302. eCollection 2024 Jan-Feb.
The coexistence of more than one chronic condition is called multimorbidity. Polypharmacy is defined as the use of multiple medicines with the typical definition stating 5 or more medications. There are several risk factors associated with polypharmacy and it may occur due to many reasons. Polypharmacy has been associated with multiple negative outcomes including nonadherence to treatment, side effects, drug-drug or disease interactions, falls, fractures, impairments-physical and cognitive, and medical errors. Strategies to assess and address polypharmacy are necessary, and lifestyle medicine is shown to play a role in improving health outcomes even when polypharmacy exists.
一种以上慢性病并存的情况被称为多病共存。多重用药被定义为使用多种药物，典型的定义是使用5种或更多药物。多重用药存在几个风险因素，其发生可能有多种原因。多重用药与多种负面后果相关，包括治疗依从性差、副作用、药物相互作用或疾病相互作用、跌倒、骨折、身体和认知功能损害以及医疗差错。评估和应对多重用药的策略是必要的，并且生活方式医学已被证明即使在存在多重用药的情况下也能在改善健康结局方面发挥作用。
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