Cewers Adam, Sunnerhagen Torgny, Gilje Patrik, Wannheden Fredrik, Bläckberg Jonas, Wierup Per, Larsson Mårten, Rasmussen Magnus
Division of Infection Medicine, Helsingborg Hospital, Helsingborg, Sweden.
Division of Infection Medicine, Department of Clinical Sciences Lund, Lund University, Lund, Sweden.
IDCases. 2024 Jul 31;37:e02049. doi: 10.1016/j.idcr.2024.e02049. eCollection 2024.
is a skin commensal bacterium that can contaminate blood cultures. It is however also a rare cause of infective endocarditis (IE). Here we report a case of aortic prosthesis IE in a 76-year-old man where only a single blood culture bottle was positive initially. is a very rare cause of IE, only reported two times previously. The diagnosis in our case was confirmed by repeated blood culture positivity and eventually by detection of DNA from on heart valves after valve exchange surgery. At surgery an aortic root abscess was detected and the valve was replaced by a homograft. Recovery was complicated by antibiotic-induced nephrotoxicity and treatment was concluded with moxifloxacin in combination with rifampicin. Recovery was uneventful. This case demonstrates that growth in even a single blood culture bottle may be important in patients with prosthetic heart valves.
是一种可污染血培养的皮肤共生细菌。然而，它也是感染性心内膜炎（IE）的罕见病因。在此，我们报告一例76岁男性主动脉人工瓣膜心内膜炎病例，最初仅有一个血培养瓶呈阳性。是IE的极为罕见的病因，此前仅报道过两次。我们病例的诊断通过反复血培养阳性得以证实，最终通过瓣膜置换手术后从心脏瓣膜检测到的DNA得以确认。手术时发现主动脉根部脓肿，瓣膜被同种异体移植物替代。恢复过程因抗生素诱导的肾毒性而复杂化，治疗以莫西沙星联合利福平结束。恢复过程顺利。该病例表明，即使在单个血培养瓶中生长，对于人工心脏瓣膜患者也可能很重要。
