McDuffie F C
Am J Med. 1985 Jan 21;78(1A):1-5. doi: 10.1016/0002-9343(85)90237-2.
Classic and definite rheumatoid arthritis affects from 0.5 to 1 percent of the United States' population between the ages of 20 and 80. In the age group of 55 to 75 years, this figure increases to 4.5 percent. In addition to the pain and suffering produced by this disease, family structure is dramatically affected--the divorce rate for patients with rheumatoid arthritis is 70 percent above that for the general population. Rheumatoid arthritis also results in serious economic loss to society. In 1983, the direct cost (out-of-pocket expense for medical care) was $777 million, and the indirect cost (loss of productivity) was $215 million, with a total of approximately $1 billion. The average person with stage III rheumatoid arthritis suffers a 60 percent decline in earnings during the first six years after onset of the disease. Recent studies have indicated that the ability to remain employed depends at least as much on job-related factors as on the extent of disease or success of medical treatment. Job autonomy or the ability to control one's working conditions is the most important factor. Other important variables are education, seniority, and work that is not excessively physically demanding. Good transportation between home and job is also an essential requirement for remaining employed. There are few data available on the cost/benefit ratio of the treatment of rheumatoid arthritis. An 18-month study showed a trend toward greater improvement in patients given optimal care by a team of experts in a medical center as compared with average treatment provided in the community. A study in Scotland on cost of hospitalization of 366 patients (about one half underwent surgery) showed cost benefits of xi 14,000 to xi 131,000 over a five- to 10-year period for those who returned to work. Patients who did not return to work incurred medical costs of xi 100,000. There is little question that more effective medical treatment and better rehabilitation strategies for people with rheumatoid arthritis would provide significant benefits for patients, their families, and society.
典型且明确的类风湿性关节炎影响着美国20至80岁人群中0.5%至1%的人口。在55至75岁的年龄组中,这一数字增至4.5%。除了这种疾病所带来的痛苦外,家庭结构也受到极大影响——类风湿性关节炎患者的离婚率比普通人群高出70%。类风湿性关节炎还给社会造成了严重的经济损失。1983年,直接成本(医疗护理的自付费用)为7.77亿美元,间接成本(生产力损失)为2.15亿美元,总计约10亿美元。患有III期类风湿性关节炎的普通人在发病后的头六年里收入会下降60%。最近的研究表明,能否继续工作至少在很大程度上取决于与工作相关的因素,而非疾病的严重程度或医疗治疗的效果。工作自主性或控制自身工作条件的能力是最重要的因素。其他重要变量包括教育程度、资历以及对体力要求不过高的工作。家庭与工作地点之间良好的交通也是继续工作的一项基本要求。关于类风湿性关节炎治疗的成本效益比,可用数据很少。一项为期18个月的研究显示,与社区提供的一般治疗相比,在医疗中心由专家团队提供最佳护理的患者有更大改善的趋势。苏格兰一项对366名患者(约一半接受了手术)住院费用的研究表明,对于那些重返工作岗位的患者,在五至十年期间成本效益为1.4万至13.1万英镑。未重返工作岗位的患者产生了10万英镑的医疗费用。毫无疑问,为类风湿性关节炎患者提供更有效的医疗治疗和更好的康复策略将为患者及其家庭和社会带来显著益处。