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1型阿诺德-基亚里畸形以紧张症为特征的罕见病例。

A Rare Case of Arnold Chiari Malformation Type 1 Presenting With Features of Catatonia.

作者信息

Duraisamy Janani, Jetty Ramya Rachel, C Sivabackiya, Kaki Aruna, R Arul Saravanan

机构信息

Psychiatry, Sri Ramaswamy Memorial (SRM) Medical College Hospital and Research Centre, Chennai, IND.

Psychiatry, Sri Ramaswamy Memorial (SRM) Medical College Hospital and Research Centre, Kattankulathur, IND.

出版信息

Cureus. 2024 Jul 24;16(7):e65321. doi: 10.7759/cureus.65321. eCollection 2024 Jul.

DOI:10.7759/cureus.65321
PMID:39184746
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11344194/
Abstract

The Arnold Chiari malformation is a congenital neurological condition. It occurs due to a defect in the cerebellum. Our patient is a 19-year-old postpartum female who presented to our ER with headaches, crying spells, reduced interaction, poor self-care, and neglect of her newborn for the past five days. Before the onset of her presenting symptoms, the patient had complained of a severe headache in the back of the head and dizziness. Her baseline investigations were normal. On examination, the patient was noticed to have a fixed gaze, ambiguity, mutism, and rigidity. So, she was diagnosed with catatonia, a differential diagnosis of mental and behavioral disorders associated with pregnancy, childbirth, and puerperium, and was treated with medications appropriately. As her headache showed minimal relief with adequate analgesic measures, neuroimaging was done, which showed Arnold Chiari malformation type I with hydrocephalus. A liaison was made with the neurology team, who confirmed the diagnosis and advised her on the decompression procedure. Her family refused to undergo the procedure. Once she showed minimal improvement in her symptoms, her family members requested her discharge. In our case, the Arnold Chiari malformation type I presented with features of catatonia, unlike the usual reported presentation of depression and anxiety. This case highlights the need for a thorough evaluation of any patient presenting with catatonia.

摘要

阿诺德-奇阿里畸形是一种先天性神经疾病。它是由于小脑缺陷而发生的。我们的患者是一名19岁的产后女性,在过去五天里因头痛、哭闹、互动减少、自我照顾能力差以及忽视新生儿而前来我们的急诊室就诊。在出现当前症状之前,患者曾抱怨后脑勺严重头痛和头晕。她的基线检查结果正常。经检查,发现患者有凝视固定、言语含糊、缄默和强直症状。因此,她被诊断为紧张症,这是一种与妊娠、分娩和产褥期相关的精神和行为障碍的鉴别诊断,并接受了适当的药物治疗。由于采取了充分的止痛措施后她的头痛缓解甚微,于是进行了神经影像学检查,结果显示为I型阿诺德-奇阿里畸形伴脑积水。与神经科团队进行了联络,他们确认了诊断并就减压手术向她提供了建议。她的家人拒绝接受该手术。一旦她的症状稍有改善,她的家人就要求让她出院。在我们的病例中,I型阿诺德-奇阿里畸形表现出紧张症的特征,这与通常报道的抑郁和焦虑表现不同。这个病例凸显了对任何出现紧张症的患者进行全面评估的必要性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a70/11344194/8c1eee631ef1/cureus-0016-00000065321-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a70/11344194/99384070395c/cureus-0016-00000065321-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a70/11344194/45ab1ce6aba2/cureus-0016-00000065321-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a70/11344194/8c1eee631ef1/cureus-0016-00000065321-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a70/11344194/99384070395c/cureus-0016-00000065321-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a70/11344194/45ab1ce6aba2/cureus-0016-00000065321-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2a70/11344194/8c1eee631ef1/cureus-0016-00000065321-i03.jpg

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本文引用的文献

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Postpartum psychosis: A proposed treatment algorithm.产后精神病:一种治疗算法的建议。
J Psychopharmacol. 2023 Oct;37(10):960-970. doi: 10.1177/02698811231181573. Epub 2023 Jul 29.
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Catatonia: demographic, clinical and laboratory associations.紧张症:人口统计学、临床和实验室关联。
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An examination of pain, disability, and the psychological correlates of Chiari Malformation pre- and post-surgical correction.对 Chiari 畸形术前和术后疼痛、残疾和心理相关因素的研究。
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The cerebellum and cognition.小脑与认知。
Neurosci Lett. 2019 Jan 1;688:62-75. doi: 10.1016/j.neulet.2018.07.005. Epub 2018 Jul 8.
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Major depressive disorder comorbid severe hydrocephalus caused by Arnold-Chiari malformation.阿诺德-奇亚里畸形合并严重脑积水所致的重度抑郁症
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Catatonia Under-Diagnosis in the General Hospital.综合医院中紧张症的诊断不足。
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Atlantoaxial Fixation for Chiari 1 Formation in Pediatric Age-Group Patients: Report of Treatment in 33 Patients.小儿寰枢椎固定治疗Chiari 1畸形:33例患者的治疗报告
World Neurosurg. 2018 Mar;111:e668-e677. doi: 10.1016/j.wneu.2017.12.137. Epub 2017 Dec 30.
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