Khan Mohd Aswad, Rahman Sajjad Abdur, Danish Mohammad, Afrose Ruquiya
Department of Oral and Maxillofacial Surgery, Dr Ziauddin Ahmad Dental College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
Department of Pathology, Jawaharlal Nehru Medical College, Aligarh Muslim University, Aligarh, Uttar Pradesh, India.
Int J Clin Pediatr Dent. 2024 Feb;17(2):202-205. doi: 10.5005/jp-journals-10005-2763.
Tuberculosis (TB), also known as Koch's disease, is a chronic granulomatous disease typically caused by (). On 24 March 1882, Dr Robert Koch discovered that caused TB. In humans, and atypical mycobacterium may also cause this disease. According to the World Health Organization (WHO) Global Report 2022, published on 27 October 2022, the incidence of TB in India for the year 2022 is 210/100,000 population. Primarily, TB affects the pulmonary region in humans, whereas secondarily, it may affect extrapulmonary sites such as the bones and intestines via lymph nodes. In this article, we are reporting a rare case of tubercular osteomyelitis of the mandible, in which the patient reported swelling of the cheek, mimicking an odontogenic infection that led to mandibular osteomyelitis. The definitive diagnosis of tubercular osteomyelitis was made by cartridge-based nucleic acid amplification test (CB-NAAT) when the cheesy material was found during surgical debridement and curettage of the mandible. Following that diagnosis, antitubercular treatment (ATT) was started immediately for the patient, which led to the complete resolution of the disease. The patient has been on regular follow-up for the last six months with no evidence of relapse of disease. Primary TB of the mandible is very rare, with only a few reported cases in the literature.
Khan MA, Rahman SA, Danish M, A Rare Case of Tubercular Osteomyelitis of Mandible in a 5-year-old Child. Int J Clin Pediatr Dent 2024;17(2):202-205.
结核病（TB），也称为科赫氏病，是一种慢性肉芽肿性疾病，通常由（）引起。1882年3月24日，罗伯特·科赫博士发现了导致结核病的（）。在人类中，（）和非典型分枝杆菌也可能引起这种疾病。根据世界卫生组织（WHO）2022年10月27日发布的《2022年全球报告》，2022年印度的结核病发病率为每10万人口210例。主要地，结核病在人类中影响肺部区域，其次，它可能通过淋巴结影响肺外部位，如骨骼和肠道。在本文中，我们报告了一例罕见的下颌骨结核性骨髓炎病例，该患者报告脸颊肿胀，类似牙源性感染，导致下颌骨骨髓炎。当在下颌骨手术清创和刮除术中发现干酪样物质时，通过基于试剂盒的核酸扩增试验（CB - NAAT）做出了结核性骨髓炎的明确诊断。在做出该诊断后，立即为患者开始抗结核治疗（ATT），这导致疾病完全缓解。在过去的六个月里，该患者一直在定期随访，没有疾病复发的迹象。下颌骨原发性结核病非常罕见，文献中仅有少数病例报道。
Khan MA, Rahman SA, Danish M, 一名5岁儿童下颌骨结核性骨髓炎的罕见病例。《国际临床儿科牙科杂志》2024；17(2):202 - 205。
