Altemeemy Issa, Alibrahim Nassar T, Alzajaji Qusay B, Mansour Abbas A
Faiha Specialized Diabetes, Endocrine and Metabolism Center (FDEMC), College of Medicine, University of Basrah, Basrah, IRQ.
Diabetes and Endocrinology, Alhassan Metabolism, Endocrine and Diabetes Center (HMEDC), Karbala, IRQ.
Cureus. 2024 Aug 23;16(8):e67609. doi: 10.7759/cureus.67609. eCollection 2024 Aug.
Background Hypertriglyceridemia (HTG) is one of the major modifiable risk factors for the development of several metabolic diseases. Determining the factors associated with HTG is an important step for increasing awareness of the problem and proper planning of health programs for HTG prevention. This study aimed to determine the conditions associated with HTG in adult patients in Basrah, Iraq. Methodology This retrospective study was conducted at Faiha Specialized Diabetes Endocrine and Metabolism Center (FDEMC) in Basra, southern Iraq, in January 2024. The data were retrieved from the center database of 37,133 subjects registered from 2008 to 2023 (16,284, 43.8% males and 20,849, 56.2% females) who attended the FDEMC in Basra due to different reasons. Results The most common causes of HTG were type 2 diabetes mellitus (T2DM) (29,799, 80%), obesity (19,914, 53.63%), and smoking (7,309, 12.68%). The age group of 18-45 years displayed higher triglyceride (TG) levels (281.1 ± 210.1 mg/dL) than other age groups. Furthermore, male patients had higher TG levels than females (288.0 ± 196.3 mg/dL vs. 268.9 ± 165.9 mg/dL). Regarding body mass index, overweight and obese patients had higher mean TG levels (284.4 ± 182.1 mg/dL and 281.7 ± 184.6 mg/dL, respectively). Current and ex-smokers had higher TG levels (305.1 ± 212.2 mg/dL and 283.4 ± 161.3 mg/dL, respectively) than non-smokers (272.5 ± 175.4 mg/dL). Moderate HTG was the most common category encountered in 24,137 patients (65%), followed by mild HTG (12,705, 34.2%). Very few patients had severe (264, 7%) or very severe HTG (27, 0.07%). Male patients had more frequent severe and very severe HTG than females. Conclusions The most common conditions associated with HTG were T2DM, obesity, and smoking. Smoker males were prone to severe and very severe HTG.
背景 高甘油三酯血症(HTG)是多种代谢性疾病发生的主要可改变风险因素之一。确定与HTG相关的因素是提高对该问题的认识以及合理规划HTG预防健康项目的重要一步。本研究旨在确定伊拉克巴士拉成年患者中与HTG相关的情况。
方法 这项回顾性研究于2024年1月在伊拉克南部巴士拉的法伊哈糖尿病内分泌与代谢专科中心(FDEMC)进行。数据从该中心数据库中检索,该数据库包含2008年至2023年登记的37133名受试者(16284名男性,占43.8%;20849名女性,占56.2%),他们因不同原因前往巴士拉的FDEMC就诊。
结果 HTG最常见的病因是2型糖尿病(T2DM)(29799例,占80%)、肥胖(19914例,占53.63%)和吸烟(7309例,占12.68%)。18至45岁年龄组的甘油三酯(TG)水平(281.1±210.1mg/dL)高于其他年龄组。此外,男性患者的TG水平高于女性(288.0±196.3mg/dL对268.9±165.9mg/dL)。就体重指数而言,超重和肥胖患者的平均TG水平较高(分别为284.4±182.1mg/dL和281.7±184.6mg/dL)。目前吸烟者和既往吸烟者的TG水平(分别为305.1±212.2mg/dL和283.4±161.3mg/dL)高于非吸烟者(272.5±175.4mg/dL)。中度HTG是最常见的类型,在24137例患者中(占65%)出现,其次是轻度HTG(12705例,占34.2%)。极少患者患有重度(264例,占7%)或极重度HTG(27例,占0.07%)。男性患者的重度和极重度HTG比女性更常见。
结论 与HTG相关最常见的情况是T2DM、肥胖和吸烟。吸烟男性更容易患重度和极重度HTG。