Maitz Joanneke, Carelli Lucas G, Coady Elizabeth, Loi Duncan, Maitz Peter
From the Department of Burns and Reconstructive Surgery, Concord Repatriation General Hospital, Concord, New South Wales, Australia.
Burns and Reconstructive Surgery Research Group, Concord Repatriation General Hospital, Concord, New South Wales, Australia.
Plast Reconstr Surg Glob Open. 2024 Aug 23;12(8):e6094. doi: 10.1097/GOX.0000000000006094. eCollection 2024 Aug.
The "work horse" for the treatment of full-thickness defects of any etiology, including chronic nonhealing wounds and traumatic injuries, is generally autologous split-thickness skin grafts (STSGs), meshed, hand-fenestrated, or a sheet graft. Advancements in skin tissue engineering have allowed for the integration of dermal substitutes to be combined with autologous STSGs, adding valuable options for restoring the skin's complex multilayered structure. Although dermal templates offer a promising avenue for more nuanced reconstruction in certain cases, their application is not without challenges, particularly when they are made from delicate materials. The following technique simplifies the application technique of single-stage dermal templates by using a composite approach. To demonstrate this technique, MatriDerm, a 1-mm-thick bovine collagen-elastin dermal template, is used to enable an STSG to be applied in a one-stage procedure.
治疗任何病因导致的全层缺损（包括慢性不愈合伤口和创伤性损伤）的“主力军”通常是自体中厚皮片（STSG），可以是网状、手工开窗或片状移植。皮肤组织工程的进展使得真皮替代物能够与自体STSG结合使用，为恢复皮肤复杂的多层结构增加了有价值的选择。尽管真皮模板在某些情况下为更精细的重建提供了一条有前景的途径，但其应用并非没有挑战，特别是当它们由精细材料制成时。以下技术通过使用复合方法简化了单阶段真皮模板的应用技术。为了演示该技术，使用了一种1毫米厚的牛胶原蛋白-弹性蛋白真皮模板MatriDerm，以使STSG能够在单阶段手术中应用。
