Maitz Joanneke, Carelli Lucas, Coady Elizabeth, Loi Duncan, Maitz Peter
From the Department of Burns and Reconstructive Surgery, Concord Repatriation General Hospital, Concord, NSW, Australia.
Burns and Reconstructive Surgery Research Group, Concord Repatriation General Hospital, Concord, NSW, Australia.
Plast Reconstr Surg Glob Open. 2025 Aug 4;13(8):e7013. doi: 10.1097/GOX.0000000000007013. eCollection 2025 Aug.
MatriDerm is frequently used with a split-thickness skin graft (STSG) in a 1-stage procedure and has been clinically shown to improve the quality and appearance of reconstructed tissue. However, its fragile nature makes it challenging to use, especially when in contact with moisture or wound exudate. Recently, a novel composite application technique was described to improve the handling and ease of use of MatriDerm in a single-stage procedure. This case series uses the new application technique and discusses its outcomes.
Four patients admitted between October 2022 and December 2022 to the burns and reconstructive surgery unit of Concord Repatriation General Hospital received MatriDerm applied with the new technique to their deep dermal and full-thickness injuries. All injuries were sustained by a burn, encompassing 1% total body surface area or less, and varied in anatomical location: shin, ankle, hand, and knee.
Complete wound closure was achieved in all patients using the new composite application technique. The method allowed for more efficient operating time, with less skin graft manipulation than the standard application technique recommended by the manufacturer.
The results demonstrate the efficacy of a composite application technique combining MatriDerm with STSGs as a 1-stage solution for deep dermal and full-thickness wound treatment, especially in challenging anatomical areas such as digits or over joints. Initial findings suggest comparable graft success rates to standard STSG results. Despite its promising outcome, further investigations with more significant case numbers are required to further evaluate its safety, efficacy, and cost-effectiveness.
MatriDerm常用于一期手术中的中厚皮片移植（STSG），临床已证明其可改善重建组织的质量和外观。然而，其质地脆弱，使用起来具有挑战性，尤其是与水分或伤口渗出液接触时。最近，一种新的复合应用技术被描述用于在一期手术中改善MatriDerm的操作性和易用性。本病例系列采用了这种新的应用技术并讨论了其结果。
2022年10月至2022年12月期间，四名入住康科德遣返总医院烧伤与重建外科的患者接受了采用新技术应用于其深度真皮和全层损伤的MatriDerm。所有损伤均由烧伤导致，占全身表面积的1%或更少，且解剖位置各异：小腿、脚踝、手部和膝盖。
使用新的复合应用技术，所有患者均实现了伤口完全闭合。该方法使手术时间更高效，与制造商推荐的标准应用技术相比，皮片操作更少。
结果证明了将MatriDerm与STSG结合的复合应用技术作为深度真皮和全层伤口治疗的一期解决方案的有效性，尤其是在手指或关节等具有挑战性的解剖区域。初步结果表明移植成功率与标准STSG结果相当。尽管结果令人鼓舞，但仍需要更多病例数的进一步研究来进一步评估其安全性、有效性和成本效益。
