Husby G, Williams R C
Arthritis Rheum. 1985 Feb;28(2):174-81. doi: 10.1002/art.1780280212.
Synovial tissues were studied, using immunofluorescence techniques, for localization of lymphocytic infiltrates and immune reactants, including C3, C5b-9, C9, and Ia antigen. Tissue distribution of interleukin-2 (IL-2) and gamma-interferon was also determined, using mouse monoclonal antibodies. IL-2 was found in association with OKT8 and OKT4 T cells, and gamma-interferon was noted in association with T cells, B cells, and macrophages. Staining both for IL-2 and for gamma-interferon was surprisingly faint in view of the intensity of lymphocytic infiltration.
利用免疫荧光技术对滑膜组织进行研究，以确定淋巴细胞浸润和免疫反应物（包括C3、C5b-9、C9和Ia抗原）的定位。还使用小鼠单克隆抗体测定了白细胞介素-2（IL-2）和γ-干扰素的组织分布。发现IL-2与OKT8和OKT4 T细胞相关，γ-干扰素与T细胞、B细胞和巨噬细胞相关。鉴于淋巴细胞浸润的强度，IL-2和γ-干扰素的染色都出奇地淡。
