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1例神经内分泌肿瘤经CT引导下肺活检后发生类癌综合征。

A case of carcinoid syndrome after CT guided lung biopsy of a neuroendocrine tumor.

作者信息

Perrin Hee Benjamin, Ihionkhan Emmanuel, Biswal Rajiv

机构信息

Hackensack Meridian School of Medicine, Department of Radiology, 340 Kingsland Street, Nutley, NJ 07110, USA.

Jersey Shore University Medical Center, Department of Radiology, 945 NJ-33, Neptune City, NJ 07753, USA.

出版信息

Radiol Case Rep. 2024 Jul 30;19(10):4426-4428. doi: 10.1016/j.radcr.2024.07.057. eCollection 2024 Oct.

DOI:10.1016/j.radcr.2024.07.057
PMID:39185434
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11342091/
Abstract

Carcinoid tumors of the lung are an uncommon malignancy that can rarely lead to carcinoid syndrome. Carcinoid tumors represent less than 1% of all lung cancers. This case describes a rare presentation in which a previously asymptomatic woman began to experience tachycardia, shortness of breath, and anxiety after biopsy of a pulmonary carcinoid tumor. Chest CT, histology, and clinical course supported the diagnosis and the patient's symptoms quickly resolved with medication. Ultimately, surgical removal of the tumor led to complete resolution of symptoms.

摘要

肺类癌肿瘤是一种罕见的恶性肿瘤,很少会导致类癌综合征。类癌肿瘤在所有肺癌中所占比例不到1%。本病例描述了一种罕见的情况,一名此前无症状的女性在肺类癌肿瘤活检后开始出现心动过速、呼吸急促和焦虑症状。胸部CT、组织学检查和临床病程支持了诊断,患者的症状通过药物治疗迅速得到缓解。最终,手术切除肿瘤使症状完全消失。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0b/11342091/87d1a1149c25/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0b/11342091/714d9ceecd07/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0b/11342091/99216f803dc3/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0b/11342091/87d1a1149c25/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0b/11342091/714d9ceecd07/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0b/11342091/99216f803dc3/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5c0b/11342091/87d1a1149c25/gr3.jpg

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本文引用的文献

1
Lung neuroendocrine tumors: A systematic literature review (Review).肺神经内分泌肿瘤:一项系统文献综述(综述)
Exp Ther Med. 2022 Feb;23(2):176. doi: 10.3892/etm.2021.11099. Epub 2021 Dec 28.
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Carcinoid syndrome: update on the pathophysiology and treatment.类癌综合征:病理生理学和治疗的最新进展。
Clinics (Sao Paulo). 2018 Aug 20;73(suppl 1):e490s. doi: 10.6061/clinics/2018/e490s.
3
Advanced typical and atypical carcinoid tumours of the lung: management recommendations.肺高级别典型和非典型类癌肿瘤:管理建议
Curr Oncol. 2018 Jun;25(Suppl 1):S86-S93. doi: 10.3747/co.25.3808. Epub 2018 Jun 13.
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Guidelines for the management of gastroenteropancreatic neuroendocrine (including carcinoid) tumours.胃肠胰神经内分泌(包括类癌)肿瘤管理指南
Gut. 2005 Jun;54 Suppl 4(Suppl 4):iv1-16. doi: 10.1136/gut.2004.053314.
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Carcinoid heart disease: the role of urinary 5-hydroxyindoleacetic acid excretion and plasma levels of atrial natriuretic peptide, transforming growth factor-beta and fibroblast growth factor.类癌性心脏病:尿5-羟吲哚乙酸排泄及血浆心房利钠肽、转化生长因子-β和成纤维细胞生长因子水平的作用
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Clin Radiol. 2001 Mar;56(3):250-1. doi: 10.1053/crad.1999.0167.
8
Carcinoid syndrome caused by an atypical carcinoid of the uterine cervix.子宫颈非典型类癌引起的类癌综合征。
J Clin Endocrinol Metab. 1999 Nov;84(11):4209-13. doi: 10.1210/jcem.84.11.6126.
9
Fatal carcinoid crisis after percutaneous fine-needle biopsy of hepatic metastasis: case report and literature review.肝转移灶经皮细针穿刺活检后发生致命性类癌危象:病例报告及文献复习
Radiology. 1990 Mar;174(3 Pt 1):751-2. doi: 10.1148/radiology.174.3.2406783.