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交叉试验设计简介。

An Introduction to the Crossover Trial Design.

机构信息

Bernadette Capili is director of the Heilbrunn Family Center for Research Nursing at Rockefeller University, New York City, and Joyce K. Anastasi is the Independence Foundation Professor of Nursing and founding director of Special Studies in Symptom Management at New York University. This manuscript was supported in part by grant No. UL1TR001866 from the National Institutes of Health's National Center for Advancing Translational Sciences Clinical and Translational Science Awards Program. Contact author and column coordinator: Bernadette Capili,

出版信息

Am J Nurs. 2024 Sep 1;124(9):40-43. doi: 10.1097/01.NAJ.0001050812.23977.85. Epub 2024 Aug 22.

DOI:10.1097/01.NAJ.0001050812.23977.85
PMID:39185982
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11534298/
Abstract

Editor's note: This is the 23rd article in a series on clinical research by nurses. The series is designed to be used as a resource for nurses to understand the concepts and principles essential to research. Each column will present the concepts that underpin evidence-based practice-from research design to data interpretation. To see all the articles in the series, go to https://links.lww.com/AJN/A204.

摘要

编者按

本文是关于护士临床研究的系列文章中的第 23 篇。本系列旨在为护士提供资源,帮助他们理解研究的基本概念和原则。每篇专栏文章都将介绍从研究设计到数据分析的循证实践的基础概念。要查看本系列中的所有文章,请访问 https://links.lww.com/AJN/A204。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa5e/11534298/a83baa4506a2/nihms-1919085-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa5e/11534298/e3d4cba69d0e/nihms-1919085-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa5e/11534298/a83baa4506a2/nihms-1919085-f0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa5e/11534298/e3d4cba69d0e/nihms-1919085-f0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/aa5e/11534298/a83baa4506a2/nihms-1919085-f0002.jpg

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本文引用的文献

1
The Architecture of a Research Study.一项研究的架构
Am J Nurs. 2023 May 1;123(5):59-62. doi: 10.1097/01.NAJ.0000933952.08188.67.
2
Efficacy Randomized Controlled Trials.疗效随机对照试验。
Am J Nurs. 2023 Mar 1;123(3):47-51. doi: 10.1097/01.NAJ.0000921808.23646.01.
3
CONSORT 2010 statement: extension to randomised crossover trials.CONSORT 2010 声明:扩展至随机交叉试验。
BMJ. 2019 Jul 31;366:l4378. doi: 10.1136/bmj.l4378.
4
Crossover design and its application in late-phase diabetes studies.交叉设计及其在晚期糖尿病研究中的应用。
J Diabetes. 2016 Sep;8(5):610-8. doi: 10.1111/1753-0407.12412.
5
What is a crossover trial?什么是交叉试验?
BMJ. 2014 May 9;348:g3191. doi: 10.1136/bmj.g3191.