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硬脊膜外间隙吻合性血管瘤新病例:病例说明

Novel case of anastomosing hemangioma of the extradural space: illustrative case.

作者信息

Fujita Shohei, Ohno Makoto, Osaki Shuhei, Sugino Hirokazu, Yoshida Akihiko, Takahashi Masamichi, Yanagisawa Shunsuke, Osawa Sho, Tsuchiya Takahiro, Narita Yoshitaka

机构信息

Departments of Neurosurgery and Neuro-Oncology, National Cancer Center Hospital, Tokyo, Japan.

Departments of Musculoskeletal Oncology and Rehabilitation, National Cancer Center Hospital, Tokyo, Japan.

出版信息

J Neurosurg Case Lessons. 2024 Aug 26;8(9). doi: 10.3171/CASE24265.

DOI:10.3171/CASE24265
PMID:39186826
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11373698/
Abstract

BACKGROUND

Anastomosing hemangiomas are benign vascular neoplasms occurring mainly in the genitourinary tract and paraspinal soft tissues. There have been no reported cases of anastomosing hemangiomas occurring in the spinal epidural space; therefore, their clinical and radiological presentations remain unclear.

OBSERVATIONS

A 55-year-old man presented with progressive back pain and motor and sensory disturbances in both lower extremities. Magnetic resonance imaging (MRI) revealed an extradural lesion at the T4-6 level that extended into the extraspinal region through the left T5-6 intervertebral foramen. Axial MRI revealed that the tumor encircled the spinal cord, with sharp horn-like ends in the intraspinal canal. The patient underwent complete tumor resection with T4-6 laminectomy and left T5-6 foraminotomy. The histopathological diagnosis was an anastomo-sing hemangioma exhibiting anastomosing proliferation of capillary vessels with hobnailed endothelial cells. His symptoms improved, and tumor control was achieved 4 months after surgery without adjuvant therapy.

LESSONS

Although rare, anastomosing hemangiomas can occur in the spinal epidural space. Radiologically, the tumors show horn-like projections encircling the spinal cord, which can be diagnostic cues. Anastomosing hemangiomas should be included in the differential diagnosis of spinal epidural tumors, especially when characteristic horn-like projections are present. https://thejns.org/doi/10.3171/CASE24265.

摘要

背景

吻合性血管瘤是一种主要发生于泌尿生殖道和脊柱旁软组织的良性血管肿瘤。目前尚无脊髓硬膜外间隙发生吻合性血管瘤的报道病例;因此,其临床和影像学表现仍不明确。

观察结果

一名55岁男性患者出现进行性背痛及双下肢运动和感觉障碍。磁共振成像(MRI)显示T4 - 6水平硬膜外病变,通过左侧T5 - 6椎间孔延伸至椎管外区域。轴位MRI显示肿瘤包绕脊髓,在椎管内有尖锐的角状末端。患者接受了T4 - 6椎板切除术和左侧T5 - 6椎间孔切开术,完整切除肿瘤。组织病理学诊断为吻合性血管瘤,表现为毛细血管吻合性增生,内皮细胞呈鞋钉样。术后4个月,患者症状改善,未行辅助治疗即实现了肿瘤控制。

经验教训

尽管罕见,但吻合性血管瘤可发生于脊髓硬膜外间隙。在影像学上,肿瘤表现为包绕脊髓的角状突起,这可作为诊断线索。吻合性血管瘤应纳入脊髓硬膜外肿瘤的鉴别诊断,尤其是当出现特征性角状突起时。https://thejns.org/doi/10.3171/CASE24265

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本文引用的文献

1
Anastomosing haemangioma of the adrenal gland: A clinicopathological series of seven cases.肾上腺吻合性血管瘤:7例临床病理系列研究
Histopathology. 2023 Nov;83(5):791-797. doi: 10.1111/his.15022. Epub 2023 Aug 8.
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Spinal Non-Hodgkin Lymphoma Mimicking Epidural Hematoma.酷似硬膜外血肿的脊柱非霍奇金淋巴瘤
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Spinal Epidural Cavernous Hemangiomas: A Clinical Series of 9 Cases and Literature Review.脊髓硬膜外海绵状血管瘤:9例临床病例系列及文献综述
Front Oncol. 2021 Mar 17;11:572313. doi: 10.3389/fonc.2021.572313. eCollection 2021.
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Anastomosing Hemangioma of the Larynx: A Unicorn among Head and Neck Tumors.喉部吻合性血管瘤:头颈部肿瘤中的独角兽。
Ann Otol Rhinol Laryngol. 2021 Mar;130(3):298-303. doi: 10.1177/0003489420943640. Epub 2020 Jul 17.
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Left Atrial Anastomosing Hemangioma Causing Recurrent Pericardial Effusion.左房吻合性血管内皮细胞瘤致反复发作性心包积液。
Ann Thorac Surg. 2020 Mar;109(3):e157-e159. doi: 10.1016/j.athoracsur.2019.06.082. Epub 2019 Aug 17.
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Anastomosing Hemangioma of the Ovary Clinically Masquerading as Epithelial Malignancy: A Rare Case Report.临床上伪装成上皮性恶性肿瘤的卵巢吻合性血管瘤:一例罕见病例报告
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Anastomosing Hemangioma: Short Review of a Benign Mimicker of Angiosarcoma.吻合性血管瘤:血管肉瘤的良性拟态简要综述。
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Imaging Appearances and Pathologic Characteristics of Spinal Epidural Meningioma.椎管硬膜外脑膜瘤的影像学表现及病理特征。
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