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本文引用的文献

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Clin Transplant. 2020 Oct;34(10):e14048. doi: 10.1111/ctr.14048. Epub 2020 Aug 29.
2
Higher rates of rejection in HIV-infected kidney transplant recipients on ritonavir-boosted protease inhibitors: 3-year follow-up study.接受利托那韦增强蛋白酶抑制剂治疗的 HIV 感染肾移植受者的排斥反应发生率更高:3 年随访研究。
Clin Transplant. 2019 Jun;33(6):e13534. doi: 10.1111/ctr.13534. Epub 2019 Apr 3.
3
Viral hepatitis: Guidelines by the American Society of Transplantation Infectious Disease Community of Practice.病毒性肝炎:美国移植感染病学会实践社区指南。
Clin Transplant. 2019 Sep;33(9):e13514. doi: 10.1111/ctr.13514. Epub 2019 Apr 14.
4
Mortality and Kidney Transplantation Outcomes Among Hepatitis C Virus-Seropositive Maintenance Dialysis Patients: A Retrospective Cohort Study.丙型肝炎病毒血清阳性维持性透析患者的死亡率和肾移植结局:一项回顾性队列研究。
Am J Kidney Dis. 2019 Jun;73(6):815-826. doi: 10.1053/j.ajkd.2018.11.009. Epub 2019 Jan 29.
5
Disparity in access to kidney allograft offers among transplant candidates with human immunodeficiency virus.艾滋病毒感染者肾移植供体获得机会不均等。
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6
Outcomes of kidney transplantation in patients with hepatitis B virus infection: A systematic review and meta-analysis.乙型肝炎病毒感染患者肾移植的结局:一项系统评价和荟萃分析。
World J Hepatol. 2018 Feb 27;10(2):337-346. doi: 10.4254/wjh.v10.i2.337.
7
Impact of Protease Inhibitor-Based Anti-Retroviral Therapy on Outcomes for HIV+ Kidney Transplant Recipients.基于蛋白酶抑制剂的抗逆转录病毒疗法对 HIV+肾移植受者结局的影响。
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Kidney Int. 2015 Aug;88(2):341-9. doi: 10.1038/ki.2015.74. Epub 2015 Mar 25.
9
Drug-drug interactions between antiretroviral and immunosuppressive agents in HIV-infected patients after solid organ transplantation: a review.HIV 感染者实体器官移植后抗逆转录病毒和免疫抑制剂药物间的药物相互作用:综述。
AIDS Patient Care STDS. 2012 Oct;26(10):568-81. doi: 10.1089/apc.2012.0169.
10
Effect of kidney transplantation on outcomes among patients with hepatitis C.肾移植对丙型肝炎患者结局的影响。
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肾移植受者,有 HIV、HBV 和既往 HCV 感染史。

Kidney transplant recipient with history of HIV, HBV, and past HCV infection.

机构信息

Nephrology and Transplantation Division, UMAE, National Medical Center of the West, Mexican Institute of Social Security, Guadalajara, Mexico.

University Center of Health Sciences, University of Guadalajara, Guadalajara, Mexico.

出版信息

AIDS Res Ther. 2024 Aug 26;21(1):57. doi: 10.1186/s12981-024-00647-y.

DOI:10.1186/s12981-024-00647-y
PMID:39187870
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11348749/
Abstract

Chronic viral infections caused by the human immunodeficiency virus (HIV), hepatitis C (HCV), and hepatitis B (HBV) are common among patients with end-stage renal disease (ESKD). These infections were once considered contraindications to kidney transplantation due to potential risks associated with long-term immunosuppression. Improved management and antiviral therapies have changed the prognosis and survival of this group of patients, along with an increased experience in transplanting people with these viral infections. We report the first successful kidney transplant in an ESKD patient on hemodialysis with a history of concomitant HIV, HCV and HBV infection in Mexico.

摘要

慢性病毒感染由人类免疫缺陷病毒(HIV)、丙型肝炎(HCV)和乙型肝炎(HBV)引起,在终末期肾病(ESKD)患者中很常见。由于长期免疫抑制相关的潜在风险,这些感染曾被认为是肾移植的禁忌症。随着在移植这些病毒感染者方面经验的增加,对这些患者的管理和抗病毒治疗的改善改变了其预后和生存。我们报告了首例在墨西哥成功进行的肾移植,受者为一名正在接受血液透析的同时合并 HIV、HCV 和 HBV 感染的 ESKD 患者。