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介入放射学在羊水栓塞管理中的突破:一例报告

Breaking Barriers in the Management of Amniotic Fluid Embolism With Interventional Radiology: A Case Report.

作者信息

Sun Amber W, Barua Priya, Benton Alexander, Do Brian

机构信息

Department of Radiology, University of Missouri - Kansas City (UMKC) School of Medicine, Kansas City, USA.

Department of Obstetrics and Gynecology, University of Missouri - Kansas City (UMKC) School of Medicine, Kansas City, USA.

出版信息

Cureus. 2024 Aug 26;16(8):e67821. doi: 10.7759/cureus.67821. eCollection 2024 Aug.

DOI:10.7759/cureus.67821
PMID:39188338
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11346806/
Abstract

Amniotic fluid embolism (AFE) is a rare obstetric emergency with a high mortality rate despite treatment. The pathogenesis likely involves inflammatory cytokines reacting to amniotic fluid in the bloodstream, causing rapid multi-organ failure and coagulopathy. Prompt recognition and supportive, multidisciplinary treatment are vital for enhancing patient outcomes. This report presents the case of a 27-year-old female with acute decompensation due to AFE. Our patient was scheduled for cesarean delivery due to high-risk placental anomalies and began demonstrating signs of AFE and severe hemorrhage shortly after delivery. She was transferred to our tertiary care center and was treated with coil embolization of the hemorrhaging uterine, iliac, and epigastric arteries, ultimately stabilizing her and saving her life. This case highlights the successful management of AFE with interventional radiological (IR) techniques.

摘要

羊水栓塞(AFE)是一种罕见的产科急症,尽管进行了治疗,死亡率仍很高。其发病机制可能涉及炎性细胞因子对血液中羊水的反应,导致快速的多器官功能衰竭和凝血病。迅速识别并给予支持性的多学科治疗对于改善患者预后至关重要。本报告介绍了一名27岁因羊水栓塞导致急性失代偿的女性病例。我们的患者因高危胎盘异常计划行剖宫产,产后不久即开始出现羊水栓塞和严重出血的迹象。她被转至我们的三级医疗中心,接受了出血的子宫、髂动脉和腹壁动脉的线圈栓塞治疗,最终病情稳定并挽救了生命。本病例突出了采用介入放射学(IR)技术成功治疗羊水栓塞的经验。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e34/11346806/9c6060fe243a/cureus-0016-00000067821-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e34/11346806/744659543fe0/cureus-0016-00000067821-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e34/11346806/e760a821401d/cureus-0016-00000067821-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e34/11346806/eda1906e7cd1/cureus-0016-00000067821-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e34/11346806/9c6060fe243a/cureus-0016-00000067821-i04.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e34/11346806/744659543fe0/cureus-0016-00000067821-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e34/11346806/e760a821401d/cureus-0016-00000067821-i02.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e34/11346806/eda1906e7cd1/cureus-0016-00000067821-i03.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4e34/11346806/9c6060fe243a/cureus-0016-00000067821-i04.jpg

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本文引用的文献

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The Anaphylactoid Syndrome of Pregnancy: Two Autopsy Cases.妊娠类过敏反应综合征:两例尸检病例
Cureus. 2023 Sep 13;15(9):e45145. doi: 10.7759/cureus.45145. eCollection 2023 Sep.
2
Toward Risk Assessment for Amniotic Fluid Embolisms.羊水栓塞的风险评估
JAMA Netw Open. 2022 Nov 1;5(11):e2242850. doi: 10.1001/jamanetworkopen.2022.42850.
3
Association of Pregnancy Characteristics and Maternal Mortality With Amniotic Fluid Embolism.妊娠特征与羊水栓塞产妇死亡率的关联。
JAMA Netw Open. 2022 Nov 1;5(11):e2242842. doi: 10.1001/jamanetworkopen.2022.42842.
4
Atropine, Ondansetron, and Ketorolac: Supplemental Management of Amniotic Fluid Embolism.阿托品、昂丹司琼和酮咯酸:羊水栓塞的辅助治疗
Ochsner J. 2022 Fall;22(3):253-257. doi: 10.31486/toj.21.0107.
5
Obstetric Disorders and Critical Illness.产科疾病及重症
Clin Chest Med. 2022 Sep;43(3):471-488. doi: 10.1016/j.ccm.2022.04.008.
6
A description of the coagulopathy characteristics in amniotic fluid embolism: a case report.羊水栓塞中凝血功能障碍特征的描述:病例报告。
Int J Obstet Anesth. 2022 Aug;51:103573. doi: 10.1016/j.ijoa.2022.103573. Epub 2022 Jun 30.
7
The role of echocardiography in amniotic fluid embolism: a case series and review of the literature.超声心动图在羊水栓塞中的作用:病例系列及文献复习。
Can J Anaesth. 2021 Oct;68(10):1541-1548. doi: 10.1007/s12630-021-02065-4. Epub 2021 Jul 26.
8
Amniotic fluid embolism syndrome: analysis of the Unites States International Registry.羊水栓塞综合征:美国国际注册中心分析。
Am J Obstet Gynecol MFM. 2020 May;2(2):100083. doi: 10.1016/j.ajogmf.2019.100083. Epub 2020 Jan 9.
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J Matern Fetal Neonatal Med. 2022 Jan;35(2):242-257. doi: 10.1080/14767058.2020.1716330. Epub 2020 Feb 3.
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