Vu Ryan, Tseng Jill, Vu Peter, Stelling Adam
Stanford University.
University of California in Irvine.
Radiol Case Rep. 2024 Aug 2;19(10):4508-4512. doi: 10.1016/j.radcr.2024.06.091. eCollection 2024 Oct.
Metastasis to the clitoris is extremely rare. Here, we report a highly unusual case of high-grade squamous cell carcinoma of the cervix metastasizing to the clitoris a year following surgery and chemoradiotherapy. The patient presented with a painless clitoral mass identified through physical examination. Magnetic resonance imaging (MRI) showed a diffusely enhancing clitoral mass with hyperintense signals on diffusion-weighted imaging (DWI) and fluid-sensitive T2-weighted (T2W) sequences. This malignant tumor was detected by fluorine-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG PET/CT) due to its high FDG uptake. Pathological examination confirmed clitoral metastasis. Clitoral metastasis, although exceedingly rare, should be considered in cervical cancer patients presenting with clitoral masses on physical examination and imaging, particularly in those with advanced stages. Our case report is unique because it represents a recurrence in a patient initially diagnosed with early-stage cancer.
阴蒂转移极为罕见。在此，我们报告一例极为特殊的病例，一名宫颈高级别鳞状细胞癌患者在手术及放化疗一年后出现阴蒂转移。患者经体格检查发现有无痛性阴蒂肿物。磁共振成像（MRI）显示阴蒂肿物弥漫性强化，在扩散加权成像（DWI）及液体敏感的T2加权（T2W）序列上呈高信号。由于该恶性肿瘤对氟脱氧葡萄糖摄取较高，通过氟-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（F-FDG PET/CT）检测到了它。病理检查证实为阴蒂转移。阴蒂转移虽极为罕见，但对于体格检查及影像学检查发现有阴蒂肿物的宫颈癌患者，尤其是晚期患者，应予以考虑。我们的病例报告很独特，因为它代表了一名最初诊断为早期癌症患者的复发情况。
