Luo Mingshuang, Li Geng, Gao Heyun, Zhang Wen
Department of Pediatric Surgery, Zhongnan Hospital of Wuhan University, Wuhan, China.
Front Pediatr. 2024 Aug 12;12:1442034. doi: 10.3389/fped.2024.1442034. eCollection 2024.
Fetus-in-fetu (FIF) represents an exceedingly rare disease, characterized as an encapsulated and pedunculated vertebrate neoplasm, typically lacking cerebral tissue. The prevalence shows no gender preference. Notably, FIF can cause compressive damage to adjacent organs and tissues, potentially impeding the host's development and maturation.
A four-month-old male infant was identified, during pregnancy, to have a left-sided pelvic mass on ultrasound. Subsequent evaluations suggested the mass could be a FIF, exhibiting active movement. Surgical exploration revealed that the mass's left boundary was connected to the left spermatic cord and vas deferens. Pathological analysis post-surgery showed the absence of testicular tissue, but the presence of skin tissue, cartilage-like structures, and gastrointestinal elements. Additionally, localized tissue resembling vertebrae confirmed the diagnosis of testicular FIF.
An intraperitoneal testicular FIF is extremely rare, with its cause still unknown. This groundbreaking report details the diagnosis and management of such a case. Following a FIF diagnosis, prompt surgical removal is crucial, along with regular follow-up using ultrasound and tumor markers.
胎中胎（FIF）是一种极为罕见的疾病，其特征为一种有包膜且带蒂的脊椎动物肿瘤，通常缺乏脑组织。发病率无性别差异。值得注意的是，FIF可对相邻器官和组织造成压迫性损害，可能阻碍宿主的发育和成熟。
一名4个月大的男婴在孕期超声检查时被发现左侧盆腔有一肿块。后续评估提示该肿块可能为FIF，且有活动迹象。手术探查发现肿块的左边界与左侧精索和输精管相连。术后病理分析显示无睾丸组织，但有皮肤组织、软骨样结构和胃肠道成分。此外，局部类似椎骨的组织确诊为睾丸型FIF。
腹腔内睾丸型FIF极为罕见，其病因尚不清楚。本开创性报告详细介绍了此类病例的诊断和处理。确诊FIF后，及时手术切除至关重要，同时需定期通过超声和肿瘤标志物进行随访。
