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新加坡一家三级中心对肥胖子宫内膜癌女性患者进行机器人手术的八年分析。

An eight-year analysis of robotic surgery in morbidly obese women with endometrial cancer in a tertiary center in Singapore.

作者信息

Gruhl Sabrina Lasini, Yusoff Muhammad Ashraf, Chin Hui Men Selina, Nadarajah Ravichandran

机构信息

Department of Obstetrics and Gynaecology, Singapore General Hospital, Outram Rd, 169608, Singapore.

出版信息

Eur J Obstet Gynecol Reprod Biol X. 2024 Aug 2;23:100330. doi: 10.1016/j.eurox.2024.100330. eCollection 2024 Sep.

Abstract

INTRODUCTION

Surgical management of endometrial cancer is a total hysterectomy, bilateral salphingo-oophorectomy and pelvic lymph node dissection (THBSO-PLND), which is a challenging surgery in the morbidly obese. Data on morbidly obese women undergoing robotic surgery is limited in Asia. We share our experience in Singapore and aim to demonstrate that robotic surgery is safe and effective in morbidly obese women with endometrial cancer.

MATERIALS AND METHODS

We performed a retrospective analysis of patients with BMI > 40 kg/m2, who underwent robotic surgery from January 2016 to September 2023 at the Singapore General Hospital. We recruited a total of 33 patients who underwent robotic surgery for endometrial malignancy and analysed surgical outcomes, operative complications, and survival rates.

RESULTS

The average age of patients was 53 years and mean BMI 45.7. The average operative time was 232 min and average blood loss 184 ml. 3 patients had THBSO while 27 underwent THBSO-PLND. None required conversion to laparotomy. 4 patients required a mini-laparotomy for the retrieval of bulky uterus. 12 required adhesiolysis. 6 patients had additional omentectomy done. The average inpatient stay was 4.8 days. The 1-year mortality rate is 0. However, 1 patient passed away 13 months after surgery due to complications from bowel obstruction and another passed away 39 months later due to disease recurrence. 1 patient readmitted on POD6 due to post-op ileus and another for port-site hematoma. Both were managed conservatively.

CONCLUSION

Robotic surgery is a safe and effective alternative surgical tool for women who are morbidly obese with endometrial cancer.

摘要

引言

子宫内膜癌的手术治疗是全子宫切除术、双侧输卵管卵巢切除术和盆腔淋巴结清扫术(THBSO-PLND),这对于病态肥胖患者来说是一项具有挑战性的手术。在亚洲,关于接受机器人手术的病态肥胖女性的数据有限。我们分享我们在新加坡的经验,旨在证明机器人手术对于患有子宫内膜癌的病态肥胖女性是安全有效的。

材料与方法

我们对2016年1月至2023年9月在新加坡总医院接受机器人手术、体重指数(BMI)>40kg/m²的患者进行了回顾性分析。我们共招募了33例接受机器人手术治疗子宫内膜恶性肿瘤的患者,并分析了手术结果、手术并发症和生存率。

结果

患者的平均年龄为53岁,平均BMI为45.7。平均手术时间为232分钟,平均失血量为184毫升。3例患者接受了THBSO,27例接受了THBSO-PLND。无一例需要转为开腹手术。4例患者需要进行小切口剖腹术以取出巨大子宫。12例需要进行粘连松解术。6例患者进行了附加的大网膜切除术。平均住院时间为4.8天。1年死亡率为0。然而,1例患者在术后13个月因肠梗阻并发症死亡,另一例在39个月后因疾病复发死亡。1例患者在术后第6天因术后肠梗阻再次入院,另一例因切口部位血肿再次入院。两者均采用保守治疗。

结论

对于患有子宫内膜癌的病态肥胖女性,机器人手术是一种安全有效的替代手术工具。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/61b6/11347051/265d8e149123/gr1.jpg

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